ADALIENE VERSIANE M. FERREIRA
UFMG
ANA MARIA CAETANO FARIA
UFMG
Medical Doctor (MD) by Universidade Federal de Minas Gerais (1984), master degree by Microbiologia from Universidade Federal de Minas Gerais (1989) and PhD degree by Immunology from Universidade de São Paulo (1994). Has experience in Immunology, focusing on Immunology, acting on the following subjects: mucosa, oral tolerance, tolerancia oral, infecção and cytokines. (Text informed by the author) Link Lattes: http://lattes.cnpq.br/2268635568464108
ANA PAULA DUARTE DE SOUZA
PUC
graduate at Farmácia Bioquímica Análises Clínicas from Universidade Federal de Santa Maria (2003) and master's at General Biology from Universidade Federal de Santa Catarina (2006). Has experience in Immunology, focusing on Immunology, acting on the following subjects: vacina, hiv, hsp70, abo and cancer. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/7065225247536877
ANA PAULA FERNANDES
UFMG
Possui graduação em Ciências Biológicas (1986), mestrado em Microbiologia (1990) e doutorado em Parasitologia pela Universidade Federal de Minas Gerais (1997). Mestrado e doutorado sandwish na Harvard Medical School (USA). Atualmente é pesquisadora nivel IB do Conselho Nacional de Desenvolvimento Científico e Tecnológico e Professora Titular da Universidade Federal de Minas Gerais. Orientadora dos programas de pós-graduação em Genética e Ciências Farmacêuticas da UFMG. Atua nas áreas de biologia molecular, análises clíniicas e parasitologia. Desenvolve projetos nas linhas de pesquisa de diagnóstico, vacinas e tratamento contra leishmaniose, fatores de risco associados à hipercoagulabilidade, como nas tromboses e no diabetes, e no diagnóstico e epidemiologia molecular de doenças infecciosas. Coordena projetos de cunho tecnológico, que culminaram com o desenvolvimento de produto e transferência de tecnologia da vacina Leish-Tec, contra a leishmaniose visceral canina. (Texto informado pelo autor). Link Lattes: http://lattes.cnpq.br/4864692688677667
ANA PAULA JUNQUEIRA-KIPNIS
UFG
graduate at Medicina Veterinária from Universidade Federal de Goiás (1989), master's at Immunology from Universidade de São Paulo (1991) and ph.d. at Immunology from Universidade de São Paulo (1998). (Text informed by the author). Link Lattes: http://lattes.cnpq.br/1252262903952987
ANDRE LUIZ BARBOSA BAFICA
UFSC
ANGELA CASTOLDI
USP-ICB
Has experience in Immunology, focusing on Immunology and metabolism. (Text informed by the author). http://lattes.cnpq.br/4888620545462163
ANGELICA THOMAZ VIEIRA
UFMG
Graduate at Ciências Biológicas from Faculdades Metodistas Integradas Isabela Hendrix (2006) and master's at Biochemistry from Universidade Federal de Minas Gerais (2008). Has experience in Immunology, acting on the following subjects: inflammation, cytokines, ischaemia, reperfusion and neutrophils. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/2136562526267841
ARI WAISMAN
UNIVERSITÄTSMEDIZIN
Director (Institute for Molecular Medicine) and Professor (W3)
BRUNO DE BEZERRIL ANDRADE
FIOCRUZ
graduation at Medicina from Universidade Federal da Bahia (2006) and doctorate at Pathological Anatomy and Clinical Pathology from Universidade Federal da Bahia (2010). Has experience in Medicine, focusing on Infectious and Parasitic Illnesses, acting on the following subjects: leishmania, inflammation, chemokine, saliva and infection. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/5853710848006520
BURKHARD BECHER
University of Zurich
Burkhard Becher studied Biology at the University of Cologne in Germany and specialized in Molecular Genetics and Biochemistry. In 1995, for his graduate studies he went to the Montreal Neurological Inst. at McGill University in Canada to train in Neuroimmunology with Jack Antel. His work focused on the role of microglia cells as brain-resident myeloid cells capable of instructing self-reactive T cells in the context of autoimmune neuro-inflammation. In 1999 he joined the lab of Randy Noelle at the Dartmouth Medical School to extend his work to in vivo models and transgenic mice. In 2003, he was recruited as Assistant Professor to the Neurology Department at the University Hospital of Zurich. There he continued to define the cytokine networks in inflammation. In 2008, he became full professor and chairman at the Institute of Experimental Immunology at the University of Zurich and heads the Unit for Inflammation Research.
CARLOS FREDERICO MARTINS MENCK
USP-ICB
graduate at Ciencias Biológicas from Universidade de São Paulo (1977) and ph.d. at Bioquímica from Universidade de São Paulo (1982). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms, acting on the following subjects: reparo de dna, ultravioleta, mutagenese, reparo dna and xeroderma pigmentosum. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/8043136069525312
CAROLINE FURTADO JUNQUEIRA
FIOCRUZ
Research Productivity Fellowship CNPq 2 and Affiliate Member of the Brazilian Academy of Sciences, Caroline Junqueira has a degree in Biological Sciences from PUC-MG, Master in Biochemistry from UFMG, PhD in Immunology from UFMG, Postdoctoral from the University of Notre Dame - USA and IRR / FIOCRUZ. She is currently a researcher at IRR / FIOCRUZ, where she develops projects in Immunoparasitology and Cell Biology with emphasis on Plasmodium spp infections. and Trypanosoma cruzi, as well as projects in Cancer Immunology. In addition, she is an Associate Researcher at CT Vaccines Technology Development Center and is currently at Harvard Medical School / Boston Children's Hospital - USA as Visiting Researcher. He has in his curriculum several scientific awards, including the Great Prize CAPES of Thesis 2012, Great Prize UFMG of Thesis 2012, Thereza Kipnis Award (Brazilian Society of Immunology). (Text informed by the author). Link Lattes: http://lattes.cnpq.br/9405337414047265
CLARE BRYANT
The University of Cambridge
We use multidisciplinary approaches to understand how bacteria are detected by the host (through Pattern Recognition Receptors (PRRs)), but we are also studying how PRR recognition of allergen proteins or toxic proteins produced by patients link to chronic inflammatory diseases such as allergies and Alzheimer’s disease. The host has many Pattern Recognition Receptors (PRRs), such as Toll-like receptors (TLRs) and Nod-like receptors (NLRs), that detect bacteria, such as Salmonella entericia serovar Typhimurium, and their associated molecules (such as endotoxin). We are study which PRRs detect S. Typhimurium to drive an adaptive immune responses focussing on the NLRs and their effector mechanisms. We also studying the molecular mechanisms underlying how ligands, such as endotoxin, interact with TLR4/MD2 receptor complex to recruit their adaptor signalling molecules, such as Mal and Tram, to initiate intracellular signalling. We are using FRET analysis and single molecule florescence techniques to study how TLRs and NLRs form active signalling protein complexes and recruit adaptor proteins in real-time in live cells. Allergens, such as the cat dander protein Fel D1, are readily contaminated by endotoxin and this allows them to be detected by TLR4. Prevention of host detection may prevent the onset of an allergic response. In particular we are interested in how allergens, such as the cat dander protein Fel d1 enhances TLR4 signalling and whether we can design inhibitors to prevent allergen recognition. Similarly other “toxic” proteins (amyloid beta and alpha synuclein) produced during diseases such as Alzheimer’s and Parkinson’s (respectively) can be recognised by TLR4 to induce inflammation and our research to understand the molecular basis by which host recognition of these proteins occurs may lead to new treatments for these neuroinflammatory diseases.
CLAUDIA IDA BRODSKYN
FIOCRUz
CRAIG ROY
YALE UNIVERSITY
CRISTINA BEATRIZ CAZABUENA BONORINO
UFCSPA
Holds a bachelor's degree in Biological Sciences from the Federal University of Rio Grande do Sul (1988), a Masters in Genetics and Molecular Biology -UFRGS (1991) and a PhD in Immunology - UFRGS and University of Colorado (1995). Received postdoctoral degrees at the National Jewish Center for Immunology in Colorado, in autoimmunity, and at the Universities of Minnesota, and UCSD in San Diego, in memory T. Was a Full Professor at the Pontifical Catholic University of Rio Grande do Sul in the area of Cellular Immunology, and Stress Response. Coordinated the Laboratory of Immunology of Stress, School of Sciences at PUCRS. Is currently Full Professor at UFCSPA, coordinating the Immunotherapy Lab. Works in vaccine development, tumor immunology, viral immunology, transplants, and immunotherapy. Since 2011 he has been a member of the Board of the Cell Stress Society International. Is a member of the editorial board of the Brazilian Journal of Medical and Biological Research and Cell Stress and Chaperones, and an Assistant Researcher in the Department of Surgery of the School of Medicine of UCSD, USA. Academic Google: Citations: 1602; h-index: 25; i10-index: 37 (Text informed by the author). Link Lattes: http://lattes.cnpq.br/4152545470767003
CRISTINA RIBEIRO DE BARROS CARDOSO
FMRP-USP
graduate at Odontology from Universidade Federal de Uberlândia (1999), master's at Immunology from Universidade Federal de Uberlândia (2003) and ph.d. at Applied Imunology from Universidade de São Paulo (2006). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: cytokines, chemokines, fatty acids, peanut and ibd. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/0899048830187429
DANIEL YOUSSEF BARGIERI
USP-icb
DAN LITTMAN
NYU
DARIO SIMÕES ZAMBONI
FMRP-USP
DOUGLAS GOLENBOCK
University of Massachusetts
My lab has a long-standing interest in innate immune activation. Our group was one of the first in the world to study Toll receptors. Subsequently, our group has developed one of the largest and best reagent collections of any lab in the world to investigate issues related to innate immunity, including over 120 knockout mouse lines (not including mice with multiple KOs and transgenes), hundreds of transformed macrophage cell lines, cDNAs, purified ectodomains of TLRs and more. Although I am an adult Infectious Diseases specialist, my major interests are in the basic mechanisms of inflammation.
EDUARDO AMARAL
NIH
My studies focus on the immune response against Mycobacterium tuberculosis (Mtb) infection and tissue necrosis during severe forms of tuberculosis. Specifically, I have interest in the host and pathogen interaction and how this relationship may impact the fatal outcome of tuberculosis. Much of my work has focused on the role of danger signal signaling and its implication on the induction of cytolytic cell death in promoting immunopathology. Early in my career, I made the observation that different clinical isolates of mycobacteria show different virulence and distinct ability to modulate and evade the host immune response. I described that hypervirulent mycobacteria proliferate rapidly inside of macrophages inducing cytolytic cell death and massive tissue destruction. Danger signals are released to extracellular milieu such as ATP, as a result of the Mtb-induced necrotic cell death, which in turn activate purinergic receptors (P2x7) and ultimately sensitize neighbor cells to die through necrosis. More recently, I have described the role of ferroptosis, a cytolytic form of cell death characterized by intracellular iron accumulation and lipid peroxidation, in Mtb infection in vitro and in vivo. I also have interest in identifying potential targets to be approached as host direct therapy in tuberculosis.
ELENA A. LEVASHINA
MPIIB
ELIZABETH PACHECO BATISTA FONTES
UFV
HELDER NAKAYA
USP
Helder Nakaya is an assistant professor at Emory University School of Medicine in the Department of Pathology. He has a PhD in Molecular Biology with extensive training in Bioinformatics. He is an expert in Systems Vaccinology, an interdisciplinary field that combines systems-wide measurements, networks, and predictive modeling in the context of vaccines and infectious disease. Dr. Nakaya has developed systems biology approaches to understand and predict the mechanisms of vaccine induced-immunity for Yellow Fever, seasonal Influenza, Meningococcal, and Tularemia vaccines. Additionally, Dr. Nakaya is a newly appointed professor at the University of Sao Paulo, Brazil, in the Department of Clinical Analyses and Toxicology, Institute of Pharmaceutical Science. His lab will focus on investigating the basis of infectious diseases using computational systems biology. Website: www.csbiology.com (Text informed by the author). Link Lattes: http://lattes.cnpq.br/5515247461567730
HENRIQUE BORGES DA SILVA
University of Minnesota
I am a PhD at Institute for Biomedical Sciences, USP - Department of Immunology. I am graduated at Biological Sciences for University of Sao Paulo. I have experience in Physiology and Immunology, with emphasis in General Physiology, Parasite Immunology and Parasitology. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/9353814744131201
IRENE DA SILVA SOARES
USP
graduate at Biomedicina from Universidade Federal do Pará (1983), master's at Microbiology from Universidade Federal de Minas Gerais (1991) and ph.d. at Microbiology from Universidade Federal de São Paulo (1998). Has experience in Parasitology, focusing on Parasitology, acting on the following subjects: malaria, plasmodium vivax, msp-1, ama-1 and msp1. (Text informed by the author). Link Lattes: http://lattes.cnpq.br
ISAAC CHIU
Harvard Medical School
ISABELLA RAUCH
Oregon Health & Science University
Independent research lab on epithelial barrier immunity.
ITALO DO VALLE
Northeastern University
Italo Faria do Valle received his PhD in Biochemical and Biotechnological Sciences from the University of Bologna (Italy) in 2017. He later continued in his post-doctoral training at the Northeastern University, in Boston, and now he is an Associate Research Scientist at the same institution. His research involves developing computational methods for analysis and interpretation of complex biological systems, combining tools from Computational Biology, Network Science and Statistics. Before studying in Bologna, Italo received his B.S degree in Biological Sciences and the MSc degree in Bioinformatics, both from the Federal University of Minas Gerais, Brazil.
JEAN-LUC IMLER
UNISTRA
JEAN PIERRE SCHATZMANN PERON
USP-ICB
has graduation at Farmácia-Bioquímica by Universidade Estadual de Londrina (2003) , specialization at Biologia Aplicada a Saúde by Universidade Estadual de Londrina (2003) , Ph.D. at Imunologia by Universidade de São Paulo (2008) , Postdoctorate by Universidade de São Paulo (2010) and Postdoctorate by Universidade de São Paulo (2011) . Currently is of Universidade de São Paulo, Membro de comitê assessor of Ministério da Saúde e Pesquisador Associado of Plataforma Científica Pasteur-USP. Has experience in the area of Immunology. Focused, mainly, in the subjects: neuroimunologia, ZIKA, EAE. (Text automatically generated by the application CVLattes). Link Lattes: http://lattes.cnpq.br/8556721425351491
JOAO BATISTA CALIXTO
CIENP
JOAO PAULO DE BIASO VIOLA
INCA
JOÃO SANTANA DA SILVA
FMRP-USP
JOÃO TRINDADE MARQUES
UFMG
I have been interested in understanding virus-host interactions throughout my career. During my post-doctoral training, I turned my focus to the study of virus infections using the fruit fly Drosophila melanogaster as a model. This experience turned my attention to the importance of insects, which represent the most diverse group of multicellular organisms on earth. Insects have beneficial roles for our society such as pollination but can also be detrimental by transmitting viruses and other pathogens to humans and livestock worldwide. The goal of my laboratory is to understand mechanisms of virus-host interactions in insects that could eventually help control vector-borne diseases. We are especially interested in studying antiviral immunity in Aedes aegypti mosquitoes that are important insect vectors for viruses such as Dengue and Zika. Our research is currently focused on two major questions: i) How insects recognize and fight virus infections? We are currently characterizing defense mechanisms that play a role in the control of viral infection in mosquitoes. In addition, we take advantage of an important model organism, the fruit fly Drosophila melanogaster, to study different aspects of insect antiviral defense. We are especially interested in characterizing the antiviral role of RNA interference pathways, whereby virus-derived small RNAs associate with Argonaute proteins to silence viral gene expression. ii) What is the diversity of viruses circulating in mosquitoes worldwide? We are interested in characterizing the collection of viruses, the virome, found in wild insects and how these may impact host biology. Our major focus is the virome of Aedes mosquitoes since these are the major vectors for viral diseases worldwide. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/0135765503963553
JOSE CARLOS ALVES FILHO
USP
JUDY LIEBERMAN
Harvard Medical School
Judy Lieberman, MD, PhD, holds an Endowed Chair in Cellular and Molecular Medicine at Boston Children’s Hospital and is Professor of Pediatrics at Harvard Medical School. Until recently she chaired the Executive Committee of Immunology at Harvard Medical School. The Lieberman laboratory studies cytotoxic T lymphocytes and NK cells and their role in immune protection from infection and cancer. They study the molecular pathways used by killer lymphocytes to induce programmed cell death of both mammalian cells and microbes (bacteria and parasites) and the mechanisms responsible for inflammatory death (pyroptosis) triggered by innate immune recognition of invasive pathogens and danger signals. Her laboratory has also been in the forefront of developing RNAi-based therapeutics and using RNAi for genome-wide screening. They were the first to show that siRNAs could be used to treat disease in vivo and to develop cell-targeted RNAs. They have developed strategies for cell-specific delivery of siRNAs to tissues outside the liver that knockdown gene expression in vivo in T lymphocytes and cancer cells. She has received numerous awards for her research on AIDS vaccines, immunology and cancer. She is a member of the American Academy of Arts and Sciences.
KENNETH L. ROCK
UMass Medical School
One major focus of the principle investigator’s laboratory is on antigen presentation. Antigen presentation is the process whereby peptides are produced and displayed on MHC molecules to T lymphocytes. It controls whether or not T cell responses are generated and if they are, their specificity and magnitude. In addition it controls the selection of T cells during development. By controlling these events antigen presentation plays an essential role in viral host defense and indeed polymorphisms in the genes in this pathway have been linked to infectious and autoimmune diseases. Dr. Rock’s laboratory has established many of the key underlying mechanisms in these processes including the role of the proteasomes/immunoproteasomes, cytosolic aminopeptidases, and ERAP1 in MHC class I presentation, the cellular and cell biological basis of cross presentation, and the underlying mechanisms of antigen presentation in T-B cell interactions. Dr. Rock is an ISI highly cited researcher. His work has been recognized with high citation indexes (e.g. an overall H-index of 69 and a top primary paper cited >2,600 times- citation #2.b. below); paper selected and reprinted as a seminal work in the “Pillers of Immunology” series of J. of Immunology (citation #1.b, below); several commentaries in leading journals (e.g. News & Views Nature), invited reviews (e.g. Nature) and presentations at national and international meetings.
LARISSA DIAS DA CUNHA
FMRP-USP
LEONARDO HOLANDA TRAVASSOS CORRÊA
UFRJ
Bachelor's at Ciências Biológicas from Universidade do Estado do Rio de Janeiro (1997), master's at Microbiology from Universidade do Estado do Rio de Janeiro (2000) and doctorate at Microbiology from Universidade Federal do Rio de Janeiro / Institut Pasteur (2005). Post-doctoral training at the University of Toronto (2006-2010). Currently, works as Assistant Professor in the Biophysics Institute Carlos Chagas Filho at the Federal University of Rio de Janeiro. Has experience in microbiology and immunology, focusing on the innate immune system, working on the following subjects: innate immunity, NLR proteins, bacterial infection, peptidoglican and autophagy. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/0909463772935505
LIRLÂNDIA PIRES DE SOUSA
UFMG
Bachelor's at Fármácia Bioquímica Análises Clínicas from Universidade Federal de Ouro Preto (1995), master's at Microbiology from Universidade Federal de Minas Gerais (1998) and doctorate at Microbiology from Universidade Federal de Minas Gerais (2003). Has experience in Microbiology, focusing on Microbiology, acting on the following subjects: ddrt-pcr jakstat ifn, alpha -enolase unresponsive cell lines ifn, neither pkc nor pkr are implicated in vaccinia vir, analysis of c-fos mrna accumulation induced by bun and effects of protein kinase inhibitors on vv-induced. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/3938506452243804
LIS RIBEIRO DO VALE ANTONELLI
LUCAS DA SILVA FAUSTINO
MGH
LUCIANA PÁDUA TAVARES
Harvard Medical School
LUIS CARLOS DE SOUZA FERREIRA
USP
bachelor's at Ciências Biológicas from Universidade Federal do Rio de Janeiro (1978), master's at Byophysics from Universidade Federal do Rio de Janeiro (1982) and doctorate at Byophysics from Universidade Federal do Rio de Janeiro (1985). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms, acting on the following subjects: vacinas, etec, vaccines, salmonella typhimurium and adjuvantes de mucosa. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/7408984376493963
LUKE O'NEIL
TCD - The University of Dublin
Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O'Neill is co-founder of Inflazome and Sitryx, which aim to develop new medicines for inflammatory diseases. He was awarded the Royal Dublin Society / Irish Times Boyle Medal for scientific excellence, the Royal Irish Academy Gold Medal for Life Sciences, The Society for Leukocyte Biology (SLB) Dolph O. Adams award, the European Federation of Immunology Societies Medal and in 2018 the Milstein Award of the International Cytokine and Interferon Society. He is a member of the Royal Irish Academy, EMBO (European Molecular Biology Organisation) and a Fellow of the Royal Society. Luke also has a passion for communicating science to the public. He has a weekly radio slot on the Pat Kenny show on Newstalk. In 2018 he published with Gill the best-selling ‘Humanology: a scientist’s guide to our amazing existence’ . This October sees the publication also with Gill of ‘The Great Irish Science Book’, a Science book for 10-12 year olds.
MARCELO TORRES BOZZA
UFRJ
Marcelo Bozza graduated in Medicine at the State University of Rio de Janeiro, Brazil (1990), MSc in Biology of Parasites at Fundação Oswaldo Cruz, Rio de Janeiro Brazil (1993) and Ph.D. in Cell and Molecular Biology also at Fiocruz (1998). Was Research Fellow in the Department of Tropical Medicine and Hygiene, Harvard School of Public Health (1994-1996). He is currently a full professor at the Department of Immunology, Institute of Microbiology at Universidade Federal do Rio de Janeiro actively participating in teaching at undergraduate and postgraduate courses. Dr. Bozza has trained a number of undergraduate and graduate students as well as post-doctoral fellows serving as thesis advisor for 36 students (22 M.Sc. and 14 PhD). He coordinated the graduate program in Immunology and Inflammation (UFRJ), is a member of the Brazilian Society of Immunology (SBI) and was a member of the board of Immunology of CNPq. Acts as reviewer for several journals including: Journal of Clinical Investigation, Circulation, eLIFE, Blood, PNAS, Plos Pathogen, Journal of Immunology, FASEB Journal, Journal of Biological Chemestry, Eur Journal of Immunology, American Journal of Pathology, Plos Negleted Diseases. Has experience in the area of immunology, with emphasis on inflammation, innate immunity and infectious diseases. Dr. Bozza has 95 publications in international journals (ex. J. Exp Med, Nat Med, J. Clin Invest, PNAS, Blood, FASEB, J Immunol, J Biol Chem), a H index of 38 and aprox. 5400 citations. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/7762134965139023
MARCO AURÉLIO RAMIREZ VINOLO
UNICAMP
MARCUS VINÍCIUS GUIMARÃES DE LACERDA
Born in Taguatinga (Federal District), has obtained his Medical Degree by the University of Brasília (1999), Infectious Diseases Residency in the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD) (2002) and PhD in Tropical Medicine by the University of Brasília in partnership with the New York University (2007). He works as a physician in the FMT-HVD and as researcher at Instituto Leônidas & Maria Deane (FIOCRUZ-Amazonas), and also as a profesor of the Graduate Program on Tropical Medicine from the University of the Amazonas State, and adjunct professor at Kent State University. He is an expert in Infectious DIseases. He coordinates since 2017 the Institute of Clinical Research Carlos Borborema, in Manaus (Brazilian Amazon). He serves as an occasional consultant of the World Health Organization on Plasmodium vivax malaria. For some years he is actively involved in initiatives devoted to malaria elimination such as malERA, MESA and the Mesoamerica Initiative. He is also a member of the Expert Scientific Advisory Committee (ESAC) from Medicines for Malaria Venture (MMV) and WorldWide Antimalarial Resistance Network (WWARN). He has already supervised more than 50 undergraduate, master and PhD students, and pot-doctoral fellows, and has over 240 scientific publications in indexed journals. He is also a level 1 researcher from CNPq. H-index=38. Major research focuses: malaria, HIV, tuberculosis, snake bites accidents and emerging diseases. (Text informed by the author) CV Lattes: http://lattes.cnpq.br/8492376468047417
MARIA REGINA D´IMPÉRIO LIMA
USP-ICB
MAURO PERRETTI
Queen Mary University of London
Briefly describe why your experience and qualifications make you particularly well-suited for your role (e.g., PD/PI, mentor, participating faculty) in the project that is the subject of the application. Over the last decade my interests have evolved on the investigation of specific endogenous mediators and pathways (e.g. melanocortins, galectins, calcitonin and, more recently, resolvins and chemerin peptides) – mainly studied in the context of experimental and human arthritis, sepsis and reperfusion injury, all in all making an internationally recognised contribution to the resolution of inflammation research area. Presently, the focus of my research is on pro-resolving receptors attempting to understand their biology and define their signature to inform innovative therapeutic approaches to exploit the resolution concept - my long-term aim is to add Resolution Pharmacology to the textbooks of Pharmacology of next decade. To date, I have published over 350 peer-reviewed articles, with an H Factor of 91 and ~28,000 citations (Google Scholar).
MAX COOPER
Emory University School of Medicine
I am a physician/scientist with the requisite expertise, leadership skills, training, breadth of research experience, record of productivity and motivation necessary to successfully carry out the proposed research project. Providing medical care for children with unusual susceptibility to infections early in my career triggered an abiding interest in learning more about normal immune system development and function in order to explore the pathogenesis of immunological disorders, immunodeficiency diseases and lymphoid malignancies in particular. This interest has fueled my sustained effort to gain a deeper understanding of the basic organizing principles of the immune system with the goal of translational application of this information.
MIHAI G. NETEA
Radboud University
Mihai Netea was born and studied medicine in Cluj-Napoca, Romania. He completed his PhD at the Radboud University Nijmegen, The Netherlands, on studies investigating the cytokine network in sepsis. After working as a post-doc at the University of Colorado, he returned to Nijmegen where he finished his clinical training as an infectious diseases specialist, and where he currently heads the division of Experimental Medicine, Department of Internal Medicine, Nijmegen University Nijmegen Medical Center. He is mainly interested in understanding the factors influencing variability of human immune responses, the biology of sepsis and immunoparalysis in bacterial and fungal infections, and the study of the memory traits of innate immunity. He is the recipient of the Spinoza Prize 2016 and an ERC Advanced grant in 2019, and member of the Netherlands Royal Academy of Science (KNAW).
NEAL SILVERMAN
University of Massachusetts
My research is focused on understanding, in molecular detail, the mechanisms by which the innate immune response recognizes and responds to microbial challenge, as well as the mechanisms by which pathogens manipulate these responses for their own nefarious goals. Much of my research has focused on the favorite laboratory model insect, Drosophila melanogaster. This is a powerful approach because of the multitude of experimental techniques available to the Drosophila researcher, and because insects rely almost entirely on innate defenses for protection. Furthermore, the innate immune response evolved with some of the earliest metazoan creatures; consequently the insect immune response and the mammalian innate immune response utilize many highly conserved molecules, including NF-κB family transcription factors and their cognate signal transduction systems, as well as the Toll-like Receptors and CD36-like Receptors. Finally, the Drosophila immune response also serves as a model for the immune responses of other, more medically relevant insects such as the mosquito or sandfly. With colleagues and collaborators, I am regularly looking to translate basic discoveries made in the Drosophila model to mammalian systems, and the current proposal exemplifies this approach. This project is built upon results from Drosophila-based screens, detailed within the proposal. However, the entire research plan will utilize mammalian systems for more detailed studies.
NIELS O .CAMARA
USP-ICB
Graduated in Medicine from the Federal University of Ceará (1991), Master of Sciences in Medicine (Nephrology) from the Federal University of São Paulo (1997), specialization in Transplantation Immunology at the University of Tours (Diplome des Etudes Appronfodies, France, 1997-1999), PhD in Medicine (Nephrology) by the Federal University of São Paulo (2000), postdoc at Imperial College London (2000-2003) and habilitation (Livre Docencia) at the Federal University of São Paulo (Medicine) in 2006. He is currently full professor of Department of Immunology at the Institute of Biomedical Sciences at the University of São Paulo (since 2011). Visiting Professor at the University of Tours, France in 2006. The laboratory has experience in nephrology area and in cellular and applied immunology, acting on the following topics: kidney transplantation, experimental models of acute and chronic kidney diseases, ischemia and reperfusion injury, regulatory cells and stem cells in kidney diseases. More recently, the laboratory has been studying the microbiota interface, cellular metabolism and inflammation in models of autoimmunity and allo. Full member of São Paulo Research Academy.Full member of Brazilian Academy of Sciences. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/8098379714093877
PEDRO H GAZZINELLI-GUIMARAES
NIH
I started my scientific career as a student of the Laboratory of Cellular and Molecular Immunology at Rene Rachou Institute – Fiocruz, Brazil, during my undergrad in Biomedicine. Got my master’s degree in Parasitology at the Biological Sciences Institute (ICB) of the Federal University of Minas Gerais – UFMG, Brazil. PhD in Parasitology from the ICB / UFMG, with one year of pre-doctoral training at the Laboratory of Parasitic Diseases (LPD) at the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), USA. This was followed by a consulting training at the Schistosomiasis Control Initiative (SCI) based at Imperial College - London, UK; where I then became a project manager/supervisor of the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) project in Cabo Delgado, Mozambique, managed by the University of Georgia–USA. After this training in coordinating public health programs and operational research in endemic areas in Africa, I then decided to start my postdoctoral training on helminth and host interaction. I am currently a postdoctoral fellow in the LPD, NIAID, NIH, USA. I have a broad background in immunology of parasitic infections and allergic diseases, biology of helminth parasites, and global health. My research interests include: 1) biomarkers for helminth antigen-specific T cells and immunophenotyping and transcriptome signature of Th2 cells; 2) mechanisms of human and experimental type-2 immune response induced by helminths; 3) influence of helminth infections on the regulation of the immune response of allergic individuals; 4) co-infections; and 5) implementation/monitoring/evaluation of different strategies of mass drug administration programs and diagnostics development for the control of Neglected Tropical Diseases in Africa.
PEDRO MANOEL MENDES DE MORAIS VIEIRA
UNICAMP
DVM - Universidade de Brasília (2006). Master - Allergology and Clinical Immunology - UFMUSP (2009). PhD in Immunology - Universidade de São Paulo (2011). Post doctoral at the Division of Endocrinology, Metabolism and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School. Professor in Immunology at the university of Campinas. The areas of research include: immunometabolism, diabetes and obesity. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/6667440528985761
PETTER BRODIN
Karolinska Institute
https://brodinlab.com/
PHILIPP HANSBRO
University of Newcastle
ROQUE PACHECO
UFS
Graduate at Medicina from Universidade Federal da Bahia (1985), master's at Immunology from Universidade Federal da Bahia (1990) and ph.d. at Immunology from Universidade Federal da Bahia (1997). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: l. braziliensis, leishmaniose tegumentar, cutaneous leishmaniasis, gm-csf and leishmania. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/9639889172454540
RUSSELL E VANCE
University of California
SANJAY RAM
University of Massachusetts
SERGIO COSTA OLIVEIRA
UFMG-ICB
Graduate at Medicina from Universidade Federal da Bahia (1985), master's at Immunology from Universidade Federal da Bahia (1990) and ph.d. at Immunology from Universidade Federal da Bahia (1997). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: l. braziliensis, leishmaniose tegumentar, cutaneous leishmaniasis, gm-csf and leishmania. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/9639889172454540
SERGIO FERREIRA
BIOQMED-UFRJ
STUART M. LEVITZ
University of Massachusetts
Dr. Stuart M. Levitz is a Professor of Medicine and Microbiology & Physiological Systems at the University of Massachusetts Medical School. Dr. Levitz’s over 150 research publications have mostly focused on the mechanisms by which the immune system controls fungal pathogens and the strategies that fungi utilize to circumvent host defenses. Particular areas of interest include how fungal glycosylation influences immune responses, the mechanisms by which phagocytes exert antifungal activity and fungal vaccine development. Current areas of focus are the role of eosinophils in allergic airway disease and using glucan particles as a delivery system for Cryptococcus vaccines. Dr. Levitz also sees patients on the Transplant Infectious Diseases consultation service at UMassMemorial Hospital.
THIAGO MATTAR CUNHA
USP-FMRP
Has graduation at Farmácia-Bioquímica by Universidade de São Paulo (2003) , master's at Ciências Biológicas (Farmacologia) by Universidade de São Paulo (2005) , Ph.D. at Ciências Biológicas (Farmacologia) by Universidade de São Paulo (2008) , Postdoctorate by Harvard University (2019) and Postdoctorate by Universidade de São Paulo (2010) . Currently is of Universidade de São Paulo, of Universidade de São Paulo, of Universidade de São Paulo. Has experience in the area of Pharmacology , with emphasis on Farmacologia Geral. Focused, mainly, in the subjects: quimiocinas, prostaglandinas, TNFAlfa, hipernocicepção, CITOCINAS. (Text automatically generated by the application CVLattes). Link Lattes: http://lattes.cnpq.br/0585283327853481
THIAGO RENNÓ DOS MARES GUIA
BIONOVIS
TIM SPARWASSER
Johannes Gutenberg-Universität Mainz
VALÉRIA DE MATOS BORGES
FIOCRUZ
VÂNIA LUIZA DEPERON BONATO
USP-FMRP
VISHVA M. DIXIT
Genentech
Vishva M. Dixit, M.D. Vice President of Physiological Chemistry at Genentech, Inc. His interests include cell death, NF-kB signaling, role of ubiquitin modification in disease pathogenesis, and characterizing regulatory complexes within the innate immune system, especially, the Inflammasome. A historical perspective of his contributions is documented in three accounts published in Nature (2008, 453:271-273), Nature Cell Biology (2010, 12(5): 415) and The Journal of Immunology (2013, 190:3-4). He is a Foreign Member, European Molecular Biology Organization, a member of the National Academy of Medicine, the American Academy of Arts and Sciences and the National Academy of Sciences.
WILSON SAVINO
FIOCRUZ
(Frence), Doctor Honoris causa by Sorbonne Université (France) e the Luis Federico Leloir Medal (Argentinean government). He has expertise in Cellular Immunology, with emphasis in the following research areas: 1. Physiology of cell migration in the hemopoietic System; 2. Imimunoneuroendocrine interactions in health and diseases; 3) Lymphocyte migration and death in infectious diseases; 4. Lymphocyte migration in organ transplantation and autoimmune diseases; 5. Cell migration in leukemias and lymphomas; 6. Cell migration, cell therapy and immunotherapy in neuromuscular diseases. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/1217083860799906
ALEXANDER LEONARDO SILVA JUNIOR
Biomédico, Me. em Hematologia
ALEXANDRA IVO MEDEIROS
Endereço para acessar este CV: http://lattes.cnpq.br/8756770929017974 Bolsista de Produtividade em Pesquisa do CNPq - Nível PQ2. Possui graduação em Ciências Biológicas pela Universidade de São Paulo (1994), Mestrado (1998) e Doutorado (2002) em Imunologia Básica e Aplicada na FMRP-USP. Realizou seu Pós-Doutoramento na Faculdade de Ciências Farmacêuticas de Ribeirão Preto (2003-2005). Foi pesquisador PRODOC-CAPES pela Pós-graduação em Imunologia Básica e Aplicada da FMRP-USP (2006-2007). Realizou seu Pós-doutoramento pela University of Michigan (2007-2009), Division of Pulmonary and Critical Care. Atualmente é professor assistente na Faculdade de Ciências Farmacêuticas de Araraquara-UNESP. Atua na área de Imunologia celular nas seguintes áreas de pesquisa: papel imunomodulador da prostanóides na diferenciação de células TCD4+ durante o processo de fagocitose de células apoptóticas e modulação da resposta imune por mediadores lipídicos em infecções pulmonares e intestinais. (Texto informado pelo autor)
ALEXANDRE SALGADO BASSO
Endereço para acessar este CV: http://lattes.cnpq.br/6354870792125973 Graduação em Medicina Veterinária pela Universidade de São Paulo (1995), mestrado (1999) e doutorado (2004) em Patologia Experimental e Comparada pela Universidade de São Paulo. Realizou pós-doutorado no Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School entre 2005 e 2008. Atualmente é Professor Adjunto do Departamento de Microbiologia, Imunologia e Parasitologia da Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP). Tem experiência na área de Neuroimunologia e Neuroimunomodulação. (Texto informado pelo autor)
ANA MARIA CAETANO FARIA
Endereço para acessar este CV: http://lattes.cnpq.br/2268635568464108 Possui graduação em Medicina pela Universidade Federal de Minas Gerais (1984), mestrado em Microbiologia pela Universidade Federal de Minas Gerais (1989), doutorado em Imunologia pela Universidade de São Paulo (1994) e pós-doutorado pela Harvard Medical School, Boston, EUA (1998-1999 e 2003). Foi Pesquisadora Visitante na Universitá di Bologna, Itália entre setembro 2001 a fevereiro 2012. Foi membro da diretoria da Sociedade Brasileira de Imunologia, SBI (2011-2013), da Câmara de Assessoramento de Ciências Biológicas e Biotecnologia da FAPEMIG (2011-2013) e foi membro do Comitê de Acessoramento de Imunologia do CNPq (2012-2015). Atualmente é Professora Titular de Imunologia da Universidade Federal de Minas Gerais. Tem experiência na área de Imunologia, com ênfase em Imunobiologia, atuando principalmente nos seguintes temas: Imunologia de Mucosas, Imunobiologia da Nutrição, Tolerância oral, Imunobiologia do Envelhecimento. (Texto informado pelo autor)
ANA MARIA MARQUES
ANA PAULA DUARTE DE SOUZA
ANA PAULA JUNQUEIRA-KIPNIS
ANA PAULA LEPIQUE
Endereço para acessar este CV: http://lattes.cnpq.br/0808439926941946 raduada em Ciências Biológicas pela Universidade de São Paulo (1992), mestrado em Ciências Biológicas (Bioquímica) pela Universidade de São Paulo (1996) e doutorado em Ciências Biológicas (Bioquímica) pela Universidade de São Paulo (2000). Atualmente é docente no Departamento de Imunologia, no Instituto de Ciências Biomédicas, USP. Tem experiência na área de Imunologia tumoral,buscando compreender como sinais disparados por tumores influenciam a apresentação de antígenos e consequente a resposta adaptativa anti-tumoral. (Texto informado pelo autor)
ANDREAS BAUMLER
Bibliography: 1989-1992 Doktor der Naturwissenschaften (Ph.D.), Microbiology, Eberhard-Karls-Universität, Tübingen, Germany 1992-1995 Post-Doctoral Fellow, Department of Molecular Microbiology and Immunology, Oregon Health Sciences University, Portland, OR 1995-1996 Research Assistant Professor, Dept. Mol. Microbiol. & Immunol., OHSU, Portland, OR 1996-2001 Assistant Professor, Dept. Med. Microbiol. & Immunol., Texas A&M University SHSC, College Station, TX 2001-2005 Associate Professor, Dept. Med. Microbiol. & Immunol., Texas A&M University SHSC, College Station, TX 2005-present Professor, Dept. Med. Microbiol. & Immunol., University of California at Davis, Davis, CA, 2010 Elected to Fellowship in the American Academy of Microbiology 2020 Elected to Fellowship in the German National Academy of Sciences (Leopoldina)
ANDRÉ MACEDO VALE
ANDREW POLLARD
Professor Pollard is Director of the Oxford Vaccine Group in the Department of Paediatrics at the University of Oxford and an honorary consultant paediatrician at Oxford Children’s Hospital and Fellow of St Cross College. He received a knighthood in the Queen’s Birthday Honours in 2021 for services to Public Health, especially in the pandemic. His research includes the design, development and clinical evaluation of vaccines including those for typhoid, meningococcus, Haemophilus influenzae type b, pneumococcus, plague, pertussis, influenza, rabies, coronavirus and Ebola, and leads studies using a human challenge model of paratyphoid and typhoid. He runs surveillance for invasive bacterial diseases and studies the impact of pneumococcal vaccines in children in Nepal and leads a project on burden and transmission of typhoid in Nepal, Bangladesh and Malawi, and co-leads typhoid vaccine impact studies at these sites. He was the chief investigator for the clinical trials of the Oxford-AstraZeneca vaccine in 2020 in 24,000 participants in UK, South Africa and Brazil, which led to authorisation of the vaccine for use in more than 170 countries with over 550million doses distributed by July 2021. He has supervised 37 PhD students and his publications includes over 500 manuscripts and books on various topics in paediatrics and infectious diseases. He chairs the UK Department of Health and Social Care’s Joint Committee on Vaccination and Immunisation, is a member of WHO’s Strategic Advisory Group of Experts. He chaired the European Medicine’s Agency scientific advisory group on vaccines for 8 years until 2020. He received the “Science Honor and Truth Award” of the Instituto de Patologia en la Altura in La Paz, Bolivia in 2002, the Bill Marshall Award of the European Society for Paediatric Infectious Disease (ESPID) in 2013, the ESPID Distinguished Award for Education and Communication in 2015 and the Rosén von Rosenstein medal in 2019 awarded by the Swedish Paediatric Society and the Swedish Society of Medicine. He was elected to the Academy of Medical Sciences in 2016 and is an NIHR Senior Investigator. He received the Oxford University Vice Chancellor’s Innovation Award in 2020 for his work on typhoid vaccines. He made the first British ascent of Jaonli (6632m) in 1988 and Chamlang in 1991 (7309m) and was the Deputy leader of the successful 1994 British Medical Everest Expedition.
ANGELICA THOMAZ VIEIRA
BARBARA FURTADO
BARBARA LUCIA MORAIS DE OLIVEIRA VIEIRA
BARNEY GRAHAM
BURKHARD BECHER
CAMILA INDIANI DE OLIVEIRA
Endereço para acessar este CV: http://lattes.cnpq.br/5692825410779014 Possui graduação em Ciências Biológicas pela Universidade de São Paulo (1995) e doutorado em Ciências (Biologia da Relação Patógeno-Hospedeiro) pela Universidade de São Paulo (2000). É professora permanente dos cursos de pós-graduação em Patologia (UFBA-FIOCRUZ) e em Ciências da Saúde (UFBA) e professora adjunta da Fundação Bahiana Para o Desenvolvimento das Ciências. Tem experiência em Protozoologia Parasitária Humana e Leishmaniose e se dedica a estudar a interação Leishmania-Hospedeiro-Vetor. Em 2011 foi indicada a membro afiliado da Academia Brasileira de Ciências. Atualmente é Vice Diretora de Pesquisa do Instituto Gonçalo Moniz- FIOCRUZ. (Texto informado pelo autor)
CAROLINA CATTONI KOH
CAROLINE JUNQUEIRA
CLAUDIA IDA BRODSKYN
Endereço para acessar este CV: http://lattes.cnpq.br/8510726976369443 Possui graduação em Biomedicas pela Universidade Federal de São Paulo (1979), mestrado em Imunologia pela Universidade de São Paulo (1989) e doutorado em Imunologia pela Universidade de São Paulo (1996). Atualmente é Professor Titular da Universidade Federal da Bahia e Pesquisador Titular do Instituto Gonçalo Moniz, FIOCRUZ-Bahia.Exerece o mandato da presidência da Sociedade Brasileira de Imunologia no biênio 2018-2019. Tem experiência na área de Imunologia, com ênfase em Imunoparasitologia, atuando principalmente nos seguintes temas:imunidade inata e adaptativa, imunoregulação, Leishmania amazonensis, Leishmania chagasi, Leishmania braziliensis . (Texto informado pelo autor)
CRAIG ROY
CRISTINA BONORINO
CRISTINA RIBEIRO DE BARROS CARDOSO
DANIEL DE CARVALHO
Dr. De Carvalho is a renowned expert in cancer epigenomics and leads a research group at the Princess Margaret Cancer Centre and the University of Toronto. He is a pioneer in the use of cancer epigenetics combined with advanced computational approaches for developing novel liquid biopsy tools applied to cancer early detection, classification and monitoring therapy response. Dr. De Carvalho have published over 70 high profile research papers, many of those featured in prestigious scientific journals such as Nature, Science, Cell, Nature Medicine, Cancer Cell among others and was an invited speaker to over 120 talks worldwide, including such prestigious venues as the Opening plenary lecture at AACR annual meeting. For his scientific contributions, Dr. De Carvalho received numerous awards including the Canadian Cancer Society Bernard and Francine Dorval Prize, Canadian Institutes of Health Research (CIHR) Early Career Award in Cancer. He received the Canada Research Chair in Cancer Epigenetics, the Helen M Cooke Endowed Professorship and was elected membership in the 2019 cohort of The Royal Society of Canada. Most recently, Dr. De Carvalho founded and serves as CSO of Adela, a biotech company developing cell-free DNA methylation liquid biopsy technology for cancer early detection, classification and monitoring therapy response”.
DANIELE CARVALHO BERNARDO NASCIMENTO
DANIEL MANSUR
Endereço para acessar este CV: http://lattes.cnpq.br/1218389465274602 Possui graduação em Ciências Biológicas pela Universidade Federal de Minas Gerais (2002). É doutor em Ciências Biológicas (Microbiologia-ênfase em Virologia) pela Universidade Federal de Minas Gerais. Fez pós-doutorado no Imperial College London (2007-2009) tendo como principal interesse sensores de DNA da imunidade inata e o estudo da evasão do sistema imune pelo vírus Vaccinia. Foi pós-doutorando no departamento de Bioquímica e Imunologia da UFMG pesquisando as interações patógeno/hospedeiro na infecção por Dengue.Desde 2010, é Professor Adjunto de Imunologia no Departamento de Microbiologia, Imunologia e Parasitologia (MIP) na Universidade Federal de Santa Catarina. Tem como principal área de atuação a imunidade célula-intrísica e interação vírus-hospedeiro. (Texto informado pelo autor)
DAN LITTMAN
DARIO S. ZAMBONI
DAVID FURMAN
DENISE MORAIS DA FONSECA
DIEGO CARLOS REIS
DIEGO FALCI
FABIO DE CARVALHO PEIXOTO
FERNANDA CARDOSO
FERNANDA FELICE
FERNANDO Q CUNHA
FLÁVIA MESQUITA
FLÁVIO PROTÁSIO VERAS
GÉRARD EBERL
GUSTAVO GASTÃO DAVANZO
GUSTAVO P. AMARANTE-MENDES
Endereço para acessar este CV: http://lattes.cnpq.br/3033400086575581 Gustavo P. Amarante-Mendes é Professor Titular e Vice-Diretor do Instituto de Ciências Biomédicas da Universidade de São Paulo (ICB-USP). Foi Segundo Secretário (2004-2005), Vice-Presidente (2012-2013) e é o atual Presidente (2016-2017) da Sociedade Brasileira de Imunologia. É Vice-Presidente da Federação das Sociedades de Biologia Experimental (FESBE) (2017-2019). Foi Coordenador do Programa de Pós-graduação em Imunologia (2011-2015) e Presidente da Comissão Interna de Biossegurança (2009-2013) do ICB-USP. Possui graduação em Ciencias Biológicas Modalidade Médica pela Universidade de Santo Amaro (1984), mestrado (1989), doutorado (1993) e Livre-docência (2009) em Imunologia pela Universidade de São Paulo. Foi Research Associate no La Jolla Institute for Allergy and Immunology (San Diego, CA) e Visiting Scientist no Department of Genetics, Trinity College Dublin e na Genentech, Inc, uma empresa do grupo Roche. É membro do corpo editorial da Cell Death and Disease, uma revista do grupo NATURE, da Frontiers in Cell and Developmental Biology, faz parte do Editorial Advisory Panel da Biochemical Journal e é um dos Keystone Symposia Programming Consultants, desde 2012. Recebeu várias premiações científicas, entre elas o 2o Prêmio Oncologia Novartis - Saúde Brasil, Nature Review Cancer Award em 2007 (aluno de doutorado Daniel Diniz de Carvalho), Menção Honrosa no Prêmio CAPES de Tese em 2009 (aluno Ricardo Weinlich) e Premio CAPES de Tese em 2010 (aluno Daniel Diniz de Carvalho). Publicou cerca de 70 trabalhos científicos, os quais, em conjunto, apresentam mais do que 2.500 citações. Tem experiência nas áreas de Imunologia, Biologia Celular e Oncologia Experimental, atuando principalmente nos seguintes temas: morte celular, apoptose, sinalização, imunoregulação, oncogenes, leucemia mieloide crônica, melanoma. (Texto informado pelo autor)
HELDER NAKAYA
HENRIQUE BORGES DA SILVA
Henrique Borges da Silva is a Brazilian Immunologist. He has completed his Bachelor degree in Biology from the Univ. Sao Paulo (2005) and completed his PhD in Immunology in the same institution in 2014. Between 2015 and 2020 Dr. Borges da Silva was a postdoctoral fellow at Dr. Steve Jameson’s lab at the University of Minnesota. Currently, Dr. Borges da Silva is an Assistant Professor at the Mayo Clinic Department of Immunology (Arizona). Through work in his laboratory, Dr. Borges da Silva aims to understand how extracellular nucleotides regulate the immune system. Nucleotides are produced by and influence numerous intracellular pathways. In diverse circumstances, however, nucleotides are released into the extracellular environment and are sensed by specific receptors called purinergic receptors. Immune cells are not devoid of this process; many purinergic receptors are expressed by the immune system. The main focus of Dr. Borges da Silva is determining how one of these nucleotides, extracellular ATP (eATP), affects transcriptional, metabolic and functional mechanisms of CD8+ T cells in response to viral infections and cancer. This stems from fundamental discoveries made by Dr. Borges da Silva that showed a crucial role for the eATP purinergic receptor P2RX7 in the establishment of CD8-positive T cell memory.
IGOR SANTIAGO-CARVALHO
IRIS CASTRO
ISABELLA RAUCH
ISAQUE JOÃO DA SILVA DE FARIA
JEAN-LUC IMLER
Jean-Luc Imler, obtained his MSc degree from AgroParisTech in Paris in 1985 and his PhD from Strasbourg university in 1988. He then joined the DNAX Research Institute in Palo Alto, CA, to work on cytokines for his post-doctoral training. Returning to France in 1992, he first worked as a research scientist in the biotech company Transgene, before being appointed Professor of cell biology at the University of Strasbourg. J.-L. Imler is chairman of the CNRS Research Unit “Insect Models of Innate Immunity” and director of the Institute of Molecular and Cellular Biology at the University of Strasbourg. J.-L. Imler’s interests have always been on the molecular and cellular aspects of cell signaling, with a focus on the context of host-pathogen interactions. In 1994, he joined as a group leader the Insect immunity Department at CNRS chaired by Jules Hoffmann to work on the model organism drosophila. There, his group first investigated the regulation of antimicrobial peptide expression by Toll receptors, before switching to the regulation of viral infection in insects. J.-L. Imler and his group have shown that viruses are controlled by the mechanism of RNA silencing in drosophila, but also trigger inducible responses, involving the evolutionarily conserved molecule STING.
JOÃO SANTANA SILVA
JOÃO T. MARQUES
JOÃO VIOLA
JORGE KALIL
JOSÉ CARLOS ALVES-FILHO
JOSÉ LUÍS FACHI
JULIA TEIXEIRA DE CASTRO
KARINA RAMALHO BORTOLUCI
KASSIANA MAFRA BICALHO
KELEN CRISTINA RIBEIRO MALMEGRIM DE FARIAS
KELLY MAGALHÃES
KRIST HELEN ANTUNES
LARISSA CUNHA
https://orcid.org/0000-0002-1290-0263 Dr. Cunha graduated in the University of São Paulo at Dario Zamboni’s lab (2012), trained as a post-doctoral fellow at St Jude Children’s Research Hospital with Dr. Douglas Green (2014-2018) and currently holds an Assistant Professor position at University of São Paulo and a Young Investigator from FAPESP. Her laboratory focuses on the cell biology of innate immune cells, working on how signaling transduction cascades initiate, progress and ultimately regulate the function of innate immune cells upon activation of a primary function such as phagocytosis. This knowledge is used to understand the pathogenesis of inflammatory disorders and the balance between resistance and tolerance to infections. She currently investigates the role of the autophagy machinery, a bonafide mechanism of coping with metabolic stresses, in the regulation of phagocytosis and their consequences in innate immune cells.
LARISSA MARCELY GOMES CASSIANO
LEDA CASTILHO
LETÍCIA DE AQUINO PENTEADO
LÍCIA TORRES
LUCAS CARVALHO
LUCAS D. FAUSTINO
LUCAS RIZZO
Lucas Bortolotto Rizzo has a Bachelor’s degree of Biomedicine from Federal University of Rio Grande do Sul (UFRGS) and a PhD on immunology and psychiatric disorders from Federal University of São Paulo (UNIFESP). He has also four years’ experience on the corporate business helping customers making better choices as a Field Application Specialist (FAS) and Technical Sales Specialist (TSS).
LUIS CARLOS DE SOUZA FERREIRA
LUKE O'NEILL
Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O'Neill is co-founder of Sitryx, which aims to develop new medicines for inflammatory diseases. Another company he co-founded, Inflazome was recently acquired by Roche. He was awarded the Royal Dublin Society / Irish Times Boyle Medal for scientific excellence, the Royal Irish Academy Gold Medal for Life Sciences, The Society for Leukocyte Biology (SLB) Dolph O. Adams award, the European Federation of Immunology Societies Medal and in 2018 the Milstein Award of the International Cytokine and Interferon Society. He is a member of the Royal Irish Academy, EMBO (European Molecular Biology Organisation) and a Fellow of the Royal Society. Luke also has a passion for communicating science to the public. He has a weekly radio slot on the Pat Kenny show on Newstalk. In 2018 he published with Gill the best-selling ‘Humanology: a scientist’s guide to our amazing existence’ and in 2019 Gill published ‘The Great Irish Science Book’, a Science book for 10-12 year olds. His latest book, also published by Gill is called ‘Never Mind the B#ll*cks Here’s the Science’.
MANOEL BARRAL-NETTO
MARCELO TORRES BOZZA
MARCO ATAIDE
Marco obtained his Bachelor's degree in Biological Sciences in 2009 from the Pontifical Catholic University of Minas Gerais. From 2010 to 2014, Marco developed his master's and doctorate studies, being enrolled in the graduate school of the Biochemistry and Immunology Department at the Federal University of Minas Gerais. Under Prof. Dr. Ricardo Gazzinelli's supervision, he uncovered some molecular and cellular aspects of the innate immune-associated malaria pathogenesis. He has described the importance of the inflammasome activation for the septic shock-like observed during Plasmodium infection. Additionally, one of his doctorate studies unveils the cellular e molecular choreography associated with experimental cerebral malaria. In 2015, Marco started his postdoctoral training by joining the Leukocytes Dynamics lab led by Prof. Dr. Wolfgang Kastenmüller, initially located at the University of Bonn, Germany, and now at the University of Würzburg as part of the Max Planck Research Group – Systems Immunology Institute. Recently, Marco has uncovered an essential piece of the molecular network controlling the CD8+ T cell memory formation. He also has contributed to the development of new insights regarding the immunobiology of invariant T cells. In 2020, Marco returned to Brazil, where he works as a postdoctoral researcher at Prof. Dr. Dario Zamboni at the University of São Paulo Medical School – Ribeirao Preto, exploring cell death dynamics and inflammasome activation in controlling bacterial infections in vivo.
MARCO AURÉLIO RAMIREZ VINOLO
MARCO SAFADI
MARIA REGINA D´IMPÉRIO LIMA
MARTTI ANTILA
MICHAEL T. HENEKA
MONIQUE T. FONSECA
NATÁLIA BRUNETTI SILVA
NAYANE GALDINO
PATRÍCIA T. BOZZA
PAULO HENRIQUE LISBOA RAEDER
PEDRO GAZZINELLI
PEDRO M. M. M. VIEIRA
Pedro M M Moraes Vieira is a doctor of veterinary medicine by the University of Brasilia and a PhD in immunology by the University of Sao Paulo. Currently he is Associated Professor of Immunology at the University of Campinas and a researcher in the field of immunometabolism. He spent five years (2011 / 2016) as a Research Fellow at the Division of Metabolism, Endocrinology and Diabetes of the Beth Israel Deaconess Medical Center in Harvard Medical School. During this time, he worked on understanding the link between systemic physiology and macrophage immunometabolic regulation. Prof. Moraes-Vieira is the head of the Laboratory of Immunometabolism. His areas of interest are immunometabolic regulation of tissue resident macrophages in healthy and disease, such as obesity and auto-immune and inflammatory diseases.
RAFICK-PIERRE SÉKALY
RAYANE MARTINS BOTELHO
RICARDO GAZZINELLI
RUSSELL VANCE
SERGIO COSTA OLIVEIRA
I am a Full Professor of Immunology at the Federal University of Minas Gerais, Brazil and my research interest is focused on defining the role of innate immunity and inflammation during the course of the intracellular bacterial infections. I got my PhD and postdoctoral training at the University of Wisconsin-Madison (USA). Currently, I am member of the Brazilian Academy of Science and member of the World Academy of Sciences (TWAS). So far, I have published more than 210 peer-reviewed articles with more than 10,000 citations. Additionally, I have trained 23 Master's and 24 PhD's students, and 39 Post-doctoral fellows. Complete List of Published Work in My Bibliography: http://www.ncbi.nlm.nih.gov/myncbi/sergio.oliveira.1/bibliography/48868768/public/?sort=date&direction=ascending
TAMARA SIVA RODRIGUES
THAÍS DA SILVA RIGONI
THERESA RAMALHO
TIM SPARWASSER
Tim Sparwasser studied human medicine at the Johannes-Gutenberg-University Mainz and the Ludwig-Maximilians-University Munich (LMU). After his doctorate he continued his research activities at the Institute for Medical Microbiology, Immunology and Hygiene (MIH) at the Technical University of Munich (TUM) and afterwards at the Skirball Institute as Howard Hughes Medical Institute (HHMI) Postdoctoral Fellow in New York. After his habilitation in 2008 he became director of the Institute of Infection Immunology at Twincore (Center for Experimental and Clinical Infection Research) a joint venture of the Hannover Medical School and the Helmholtz Centre for Infection Research. In 2018, he followed a call from the University of Mainz and became director of the Institute of Medical Microbiology and Hygiene (IMMH) after he had declined a corresponding call from the Technical University of Dresden in 2017. Since 2014 he is a council member of the German Society of Immunology (DGfI). Since 2018, he is a member of the steering committee of the Research Center for Immunotherapy (FZI) at the University of Mainz. In 2019 he was elected as German representative to the Council of the International Union of Immunology Societies (IUIS). The main research interests of his laboratory at the Institute of Medical Microbiology and Hygiene are host-pathogen interactions. Sparwasser was one of the first to recognize that microbial DNA sequences containing specific CpG motifs activate cells of the innate immune system and can therefore be used as adjuvants in experimental vaccination approaches. Using novel genetic models, Sparwasser for the first time directly demonstrated the role of so-called regulatory T cells in the prevention of autoimmunity as well as their importance in the adaptive immune response against tumor cells and various pathogens. Since 2010 Sparwasser has been working on the immune modulatory effects of bacterial metabolites and in particular on the metabolism of immune cells to improve immune responses and vaccinations.
VALÉRIA BORGES
CV: http://lattes.cnpq.br/1527671960187811 Possui graduação em Ciencias Biologicas pela Universidade Federal do Rio de Janeiro (1995), mestrado (1998) e doutorado (2002) pelo Instituto de Biofísica Carlos Chagas Filho, UFRJ e pós-doutorado no Program of Cell Biology do National Jewish Medical and Research Center (Colorado, USA) como bolsista da Pew Latin American Fellows Program in the Biomedical Sciences (2003). Atua em pesquisa no Instituto Gonçalo Moniz e atualmente é coordenadora do Programa de Pós-Graduação em Patologia Humana (PgPAT). Vem se dedicando a estudos na área de parasitologia e biologia da inflamação com ênfase na interação vetor-patógeno-célula hospedeira na infecção por Leishmania sp. (Texto informado pelo autor)
VÂNIA LUIZA DEPERON BONATO
Endereço para acessar este CV: http://lattes.cnpq.br/1788319183446276 Graduação em Ciências Biológicas pela Universidade Federal de São Carlos (1992), Mestrado em Imunologia Básica e Aplicada pela Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRP-USP) (1995) e Doutorado em Imunologia Básica e Aplicada pela FMRP-USP (1999). Estágio no Instituto Pasteur, Paris, França (1999). Pós-Doutorado no Departamento de Bioquímica e Imunologia da FMRP-USP (2000-2002). Professora Doutora do Departamento de Bioquímica e Imunologia da FMRP-USP (2002-2013). Professora Associada do Departamento de Bioquímica e Imunologia da FMRP-USP (2013-atual) .Ano sabático / pós-doutorado sênior no Twincore - Instituto de Pesquisa em Doenças Infecciosas, em Hannover, Alemanha (2016-2017). Linha de pesquisa: Modulação da resposta inflamatória nos pulmões, com enfoque nas populações de linfócitos CD4+, populações de céulas dendríticas e de macrófagos. (Texto informado pelo autor)
VISHVA M. DIXIT
