Speakers

UFMG

UFMG

Medical Doctor (MD) by Universidade Federal de Minas Gerais (1984), master degree by Microbiologia from Universidade Federal de Minas Gerais (1989) and PhD degree by Immunology from Universidade de São Paulo (1994). Has experience in Immunology, focusing on Immunology, acting on the following subjects: mucosa, oral tolerance, tolerancia oral, infecção and cytokines. (Text informed by the author) Link Lattes: http://lattes.cnpq.br/2268635568464108

PUC

graduate at Farmácia Bioquímica Análises Clínicas from Universidade Federal de Santa Maria (2003) and master's at General Biology from Universidade Federal de Santa Catarina (2006). Has experience in Immunology, focusing on Immunology, acting on the following subjects: vacina, hiv, hsp70, abo and cancer. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/7065225247536877

UFMG

Possui graduação em Ciências Biológicas (1986), mestrado em Microbiologia (1990) e doutorado em Parasitologia pela Universidade Federal de Minas Gerais (1997). Mestrado e doutorado sandwish na Harvard Medical School (USA). Atualmente é pesquisadora nivel IB do Conselho Nacional de Desenvolvimento Científico e Tecnológico e Professora Titular da Universidade Federal de Minas Gerais. Orientadora dos programas de pós-graduação em Genética e Ciências Farmacêuticas da UFMG. Atua nas áreas de biologia molecular, análises clíniicas e parasitologia. Desenvolve projetos nas linhas de pesquisa de diagnóstico, vacinas e tratamento contra leishmaniose, fatores de risco associados à hipercoagulabilidade, como nas tromboses e no diabetes, e no diagnóstico e epidemiologia molecular de doenças infecciosas. Coordena projetos de cunho tecnológico, que culminaram com o desenvolvimento de produto e transferência de tecnologia da vacina Leish-Tec, contra a leishmaniose visceral canina. (Texto informado pelo autor). Link Lattes: http://lattes.cnpq.br/4864692688677667

UFG

graduate at Medicina Veterinária from Universidade Federal de Goiás (1989), master's at Immunology from Universidade de São Paulo (1991) and ph.d. at Immunology from Universidade de São Paulo (1998). (Text informed by the author). Link Lattes: http://lattes.cnpq.br/1252262903952987

UFSC

USP-ICB

Has experience in Immunology, focusing on Immunology and metabolism. (Text informed by the author). http://lattes.cnpq.br/4888620545462163

UFMG

Graduate at Ciências Biológicas from Faculdades Metodistas Integradas Isabela Hendrix (2006) and master's at Biochemistry from Universidade Federal de Minas Gerais (2008). Has experience in Immunology, acting on the following subjects: inflammation, cytokines, ischaemia, reperfusion and neutrophils. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/2136562526267841

UNIVERSITÄTSMEDIZIN

Director (Institute for Molecular Medicine) and Professor (W3)

FIOCRUZ

graduation at Medicina from Universidade Federal da Bahia (2006) and doctorate at Pathological Anatomy and Clinical Pathology from Universidade Federal da Bahia (2010). Has experience in Medicine, focusing on Infectious and Parasitic Illnesses, acting on the following subjects: leishmania, inflammation, chemokine, saliva and infection. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/5853710848006520

University of Zurich

Burkhard Becher studied Biology at the University of Cologne in Germany and specialized in Molecular Genetics and Biochemistry. In 1995, for his graduate studies he went to the Montreal Neurological Inst. at McGill University in Canada to train in Neuroimmunology with Jack Antel. His work focused on the role of microglia cells as brain-resident myeloid cells capable of instructing self-reactive T cells in the context of autoimmune neuro-inflammation. In 1999 he joined the lab of Randy Noelle at the Dartmouth Medical School to extend his work to in vivo models and transgenic mice. In 2003, he was recruited as Assistant Professor to the Neurology Department at the University Hospital of Zurich. There he continued to define the cytokine networks in inflammation. In 2008, he became full professor and chairman at the Institute of Experimental Immunology at the University of Zurich and heads the Unit for Inflammation Research.

USP-ICB

graduate at Ciencias Biológicas from Universidade de São Paulo (1977) and ph.d. at Bioquímica from Universidade de São Paulo (1982). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms, acting on the following subjects: reparo de dna, ultravioleta, mutagenese, reparo dna and xeroderma pigmentosum. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/8043136069525312

FIOCRUZ

Research Productivity Fellowship CNPq 2 and Affiliate Member of the Brazilian Academy of Sciences, Caroline Junqueira has a degree in Biological Sciences from PUC-MG, Master in Biochemistry from UFMG, PhD in Immunology from UFMG, Postdoctoral from the University of Notre Dame - USA and IRR / FIOCRUZ. She is currently a researcher at IRR / FIOCRUZ, where she develops projects in Immunoparasitology and Cell Biology with emphasis on Plasmodium spp infections. and Trypanosoma cruzi, as well as projects in Cancer Immunology. In addition, she is an Associate Researcher at CT Vaccines Technology Development Center and is currently at Harvard Medical School / Boston Children's Hospital - USA as Visiting Researcher. He has in his curriculum several scientific awards, including the Great Prize CAPES of Thesis 2012, Great Prize UFMG of Thesis 2012, Thereza Kipnis Award (Brazilian Society of Immunology). (Text informed by the author). Link Lattes: http://lattes.cnpq.br/9405337414047265

The University of Cambridge

We use multidisciplinary approaches to understand how bacteria are detected by the host (through Pattern Recognition Receptors (PRRs)), but we are also studying how PRR recognition of allergen proteins or toxic proteins produced by patients link to chronic inflammatory diseases such as allergies and Alzheimer’s disease. The host has many Pattern Recognition Receptors (PRRs), such as Toll-like receptors (TLRs) and Nod-like receptors (NLRs), that detect bacteria, such as Salmonella entericia serovar Typhimurium, and their associated molecules (such as endotoxin). We are study which PRRs detect S. Typhimurium to drive an adaptive immune responses focussing on the NLRs and their effector mechanisms. We also studying the molecular mechanisms underlying how ligands, such as endotoxin, interact with TLR4/MD2 receptor complex to recruit their adaptor signalling molecules, such as Mal and Tram, to initiate intracellular signalling. We are using FRET analysis and single molecule florescence techniques to study how TLRs and NLRs form active signalling protein complexes and recruit adaptor proteins in real-time in live cells. Allergens, such as the cat dander protein Fel D1, are readily contaminated by endotoxin and this allows them to be detected by TLR4. Prevention of host detection may prevent the onset of an allergic response. In particular we are interested in how allergens, such as the cat dander protein Fel d1 enhances TLR4 signalling and whether we can design inhibitors to prevent allergen recognition. Similarly other “toxic” proteins (amyloid beta and alpha synuclein) produced during diseases such as Alzheimer’s and Parkinson’s (respectively) can be recognised by TLR4 to induce inflammation and our research to understand the molecular basis by which host recognition of these proteins occurs may lead to new treatments for these neuroinflammatory diseases.

FIOCRUz

YALE UNIVERSITY

UFCSPA

Holds a bachelor's degree in Biological Sciences from the Federal University of Rio Grande do Sul (1988), a Masters in Genetics and Molecular Biology -UFRGS (1991) and a PhD in Immunology - UFRGS and University of Colorado (1995). Received postdoctoral degrees at the National Jewish Center for Immunology in Colorado, in autoimmunity, and at the Universities of Minnesota, and UCSD in San Diego, in memory T. Was a Full Professor at the Pontifical Catholic University of Rio Grande do Sul in the area of ​​Cellular Immunology, and Stress Response. Coordinated the Laboratory of Immunology of Stress, School of Sciences at PUCRS. Is currently Full Professor at UFCSPA, coordinating the Immunotherapy Lab. Works in vaccine development, tumor immunology, viral immunology, transplants, and immunotherapy. Since 2011 he has been a member of the Board of the Cell Stress Society International. Is a member of the editorial board of the Brazilian Journal of Medical and Biological Research and Cell Stress and Chaperones, and an Assistant Researcher in the Department of Surgery of the School of Medicine of UCSD, USA. Academic Google: Citations: 1602; h-index: 25; i10-index: 37 (Text informed by the author). Link Lattes: http://lattes.cnpq.br/4152545470767003

FMRP-USP

graduate at Odontology from Universidade Federal de Uberlândia (1999), master's at Immunology from Universidade Federal de Uberlândia (2003) and ph.d. at Applied Imunology from Universidade de São Paulo (2006). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: cytokines, chemokines, fatty acids, peanut and ibd. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/0899048830187429

USP-icb

NYU

FMRP-USP

University of Massachusetts

My lab has a long-standing interest in innate immune activation. Our group was one of the first in the world to study Toll receptors. Subsequently, our group has developed one of the largest and best reagent collections of any lab in the world to investigate issues related to innate immunity, including over 120 knockout mouse lines (not including mice with multiple KOs and transgenes), hundreds of transformed macrophage cell lines, cDNAs, purified ectodomains of TLRs and more. Although I am an adult Infectious Diseases specialist, my major interests are in the basic mechanisms of inflammation.

NIH

My studies focus on the immune response against Mycobacterium tuberculosis (Mtb) infection and tissue necrosis during severe forms of tuberculosis. Specifically, I have interest in the host and pathogen interaction and how this relationship may impact the fatal outcome of tuberculosis. Much of my work has focused on the role of danger signal signaling and its implication on the induction of cytolytic cell death in promoting immunopathology. Early in my career, I made the observation that different clinical isolates of mycobacteria show different virulence and distinct ability to modulate and evade the host immune response. I described that hypervirulent mycobacteria proliferate rapidly inside of macrophages inducing cytolytic cell death and massive tissue destruction. Danger signals are released to extracellular milieu such as ATP, as a result of the Mtb-induced necrotic cell death, which in turn activate purinergic receptors (P2x7) and ultimately sensitize neighbor cells to die through necrosis. More recently, I have described the role of ferroptosis, a cytolytic form of cell death characterized by intracellular iron accumulation and lipid peroxidation, in Mtb infection in vitro and in vivo. I also have interest in identifying potential targets to be approached as host direct therapy in tuberculosis.

MPIIB

UFV

USP

Helder Nakaya is an assistant professor at Emory University School of Medicine in the Department of Pathology. He has a PhD in Molecular Biology with extensive training in Bioinformatics. He is an expert in Systems Vaccinology, an interdisciplinary field that combines systems-wide measurements, networks, and predictive modeling in the context of vaccines and infectious disease. Dr. Nakaya has developed systems biology approaches to understand and predict the mechanisms of vaccine induced-immunity for Yellow Fever, seasonal Influenza, Meningococcal, and Tularemia vaccines. Additionally, Dr. Nakaya is a newly appointed professor at the University of Sao Paulo, Brazil, in the Department of Clinical Analyses and Toxicology, Institute of Pharmaceutical Science. His lab will focus on investigating the basis of infectious diseases using computational systems biology. Website: www.csbiology.com (Text informed by the author). Link Lattes: http://lattes.cnpq.br/5515247461567730

University of Minnesota

I am a PhD at Institute for Biomedical Sciences, USP - Department of Immunology. I am graduated at Biological Sciences for University of Sao Paulo. I have experience in Physiology and Immunology, with emphasis in General Physiology, Parasite Immunology and Parasitology. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/9353814744131201

USP

graduate at Biomedicina from Universidade Federal do Pará (1983), master's at Microbiology from Universidade Federal de Minas Gerais (1991) and ph.d. at Microbiology from Universidade Federal de São Paulo (1998). Has experience in Parasitology, focusing on Parasitology, acting on the following subjects: malaria, plasmodium vivax, msp-1, ama-1 and msp1. (Text informed by the author). Link Lattes: http://lattes.cnpq.br

Harvard Medical School

Oregon Health & Science University

Independent research lab on epithelial barrier immunity.

Northeastern University

Italo Faria do Valle received his PhD in Biochemical and Biotechnological Sciences from the University of Bologna (Italy) in 2017. He later continued in his post-doctoral training at the Northeastern University, in Boston, and now he is an Associate Research Scientist at the same institution. His research involves developing computational methods for analysis and interpretation of complex biological systems, combining tools from Computational Biology, Network Science and Statistics. Before studying in Bologna, Italo received his B.S degree in Biological Sciences and the MSc degree in Bioinformatics, both from the Federal University of Minas Gerais, Brazil.

UNISTRA

USP-ICB

has graduation at Farmácia-Bioquímica by Universidade Estadual de Londrina (2003) , specialization at Biologia Aplicada a Saúde by Universidade Estadual de Londrina (2003) , Ph.D. at Imunologia by Universidade de São Paulo (2008) , Postdoctorate by Universidade de São Paulo (2010) and Postdoctorate by Universidade de São Paulo (2011) . Currently is of Universidade de São Paulo, Membro de comitê assessor of Ministério da Saúde e Pesquisador Associado of Plataforma Científica Pasteur-USP. Has experience in the area of Immunology. Focused, mainly, in the subjects: neuroimunologia, ZIKA, EAE. (Text automatically generated by the application CVLattes). Link Lattes: http://lattes.cnpq.br/8556721425351491

CIENP

INCA

FMRP-USP

UFMG

I have been interested in understanding virus-host interactions throughout my career. During my post-doctoral training, I turned my focus to the study of virus infections using the fruit fly Drosophila melanogaster as a model. This experience turned my attention to the importance of insects, which represent the most diverse group of multicellular organisms on earth. Insects have beneficial roles for our society such as pollination but can also be detrimental by transmitting viruses and other pathogens to humans and livestock worldwide. The goal of my laboratory is to understand mechanisms of virus-host interactions in insects that could eventually help control vector-borne diseases. We are especially interested in studying antiviral immunity in Aedes aegypti mosquitoes that are important insect vectors for viruses such as Dengue and Zika. Our research is currently focused on two major questions: i) How insects recognize and fight virus infections? We are currently characterizing defense mechanisms that play a role in the control of viral infection in mosquitoes. In addition, we take advantage of an important model organism, the fruit fly Drosophila melanogaster, to study different aspects of insect antiviral defense. We are especially interested in characterizing the antiviral role of RNA interference pathways, whereby virus-derived small RNAs associate with Argonaute proteins to silence viral gene expression. ii) What is the diversity of viruses circulating in mosquitoes worldwide? We are interested in characterizing the collection of viruses, the virome, found in wild insects and how these may impact host biology. Our major focus is the virome of Aedes mosquitoes since these are the major vectors for viral diseases worldwide. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/0135765503963553

USP

Harvard Medical School

Judy Lieberman, MD, PhD, holds an Endowed Chair in Cellular and Molecular Medicine at Boston Children’s Hospital and is Professor of Pediatrics at Harvard Medical School. Until recently she chaired the Executive Committee of Immunology at Harvard Medical School. The Lieberman laboratory studies cytotoxic T lymphocytes and NK cells and their role in immune protection from infection and cancer. They study the molecular pathways used by killer lymphocytes to induce programmed cell death of both mammalian cells and microbes (bacteria and parasites) and the mechanisms responsible for inflammatory death (pyroptosis) triggered by innate immune recognition of invasive pathogens and danger signals. Her laboratory has also been in the forefront of developing RNAi-based therapeutics and using RNAi for genome-wide screening. They were the first to show that siRNAs could be used to treat disease in vivo and to develop cell-targeted RNAs. They have developed strategies for cell-specific delivery of siRNAs to tissues outside the liver that knockdown gene expression in vivo in T lymphocytes and cancer cells. She has received numerous awards for her research on AIDS vaccines, immunology and cancer. She is a member of the American Academy of Arts and Sciences.

UMass Medical School

One major focus of the principle investigator’s laboratory is on antigen presentation. Antigen presentation is the process whereby peptides are produced and displayed on MHC molecules to T lymphocytes. It controls whether or not T cell responses are generated and if they are, their specificity and magnitude. In addition it controls the selection of T cells during development. By controlling these events antigen presentation plays an essential role in viral host defense and indeed polymorphisms in the genes in this pathway have been linked to infectious and autoimmune diseases. Dr. Rock’s laboratory has established many of the key underlying mechanisms in these processes including the role of the proteasomes/immunoproteasomes, cytosolic aminopeptidases, and ERAP1 in MHC class I presentation, the cellular and cell biological basis of cross presentation, and the underlying mechanisms of antigen presentation in T-B cell interactions. Dr. Rock is an ISI highly cited researcher. His work has been recognized with high citation indexes (e.g. an overall H-index of 69 and a top primary paper cited >2,600 times- citation #2.b. below); paper selected and reprinted as a seminal work in the “Pillers of Immunology” series of J. of Immunology (citation #1.b, below); several commentaries in leading journals (e.g. News & Views Nature), invited reviews (e.g. Nature) and presentations at national and international meetings.

FMRP-USP

UFRJ

Bachelor's at Ciências Biológicas from Universidade do Estado do Rio de Janeiro (1997), master's at Microbiology from Universidade do Estado do Rio de Janeiro (2000) and doctorate at Microbiology from Universidade Federal do Rio de Janeiro / Institut Pasteur (2005). Post-doctoral training at the University of Toronto (2006-2010). Currently, works as Assistant Professor in the Biophysics Institute Carlos Chagas Filho at the Federal University of Rio de Janeiro. Has experience in microbiology and immunology, focusing on the innate immune system, working on the following subjects: innate immunity, NLR proteins, bacterial infection, peptidoglican and autophagy. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/0909463772935505

UFMG

Bachelor's at Fármácia Bioquímica Análises Clínicas from Universidade Federal de Ouro Preto (1995), master's at Microbiology from Universidade Federal de Minas Gerais (1998) and doctorate at Microbiology from Universidade Federal de Minas Gerais (2003). Has experience in Microbiology, focusing on Microbiology, acting on the following subjects: ddrt-pcr jakstat ifn, alpha -enolase unresponsive cell lines ifn, neither pkc nor pkr are implicated in vaccinia vir, analysis of c-fos mrna accumulation induced by bun and effects of protein kinase inhibitors on vv-induced. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/3938506452243804

MGH

Harvard Medical School

USP

bachelor's at Ciências Biológicas from Universidade Federal do Rio de Janeiro (1978), master's at Byophysics from Universidade Federal do Rio de Janeiro (1982) and doctorate at Byophysics from Universidade Federal do Rio de Janeiro (1985). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms, acting on the following subjects: vacinas, etec, vaccines, salmonella typhimurium and adjuvantes de mucosa. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/7408984376493963

TCD - The University of Dublin

Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O'Neill is co-founder of Inflazome and Sitryx, which aim to develop new medicines for inflammatory diseases. He was awarded the Royal Dublin Society / Irish Times Boyle Medal for scientific excellence, the Royal Irish Academy Gold Medal for Life Sciences, The Society for Leukocyte Biology (SLB) Dolph O. Adams award, the European Federation of Immunology Societies Medal and in 2018 the Milstein Award of the International Cytokine and Interferon Society. He is a member of the Royal Irish Academy, EMBO (European Molecular Biology Organisation) and a Fellow of the Royal Society. Luke also has a passion for communicating science to the public. He has a weekly radio slot on the Pat Kenny show on Newstalk. In 2018 he published with Gill the best-selling ‘Humanology: a scientist’s guide to our amazing existence’ . This October sees the publication also with Gill of ‘The Great Irish Science Book’, a Science book for 10-12 year olds.

UFRJ

Marcelo Bozza graduated in Medicine at the State University of Rio de Janeiro, Brazil (1990), MSc in Biology of Parasites at Fundação Oswaldo Cruz, Rio de Janeiro Brazil (1993) and Ph.D. in Cell and Molecular Biology also at Fiocruz (1998). Was Research Fellow in the Department of Tropical Medicine and Hygiene, Harvard School of Public Health (1994-1996). He is currently a full professor at the Department of Immunology, Institute of Microbiology at Universidade Federal do Rio de Janeiro actively participating in teaching at undergraduate and postgraduate courses. Dr. Bozza has trained a number of undergraduate and graduate students as well as post-doctoral fellows serving as thesis advisor for 36 students (22 M.Sc. and 14 PhD). He coordinated the graduate program in Immunology and Inflammation (UFRJ), is a member of the Brazilian Society of Immunology (SBI) and was a member of the board of Immunology of CNPq. Acts as reviewer for several journals including: Journal of Clinical Investigation, Circulation, eLIFE, Blood, PNAS, Plos Pathogen, Journal of Immunology, FASEB Journal, Journal of Biological Chemestry, Eur Journal of Immunology, American Journal of Pathology, Plos Negleted Diseases. Has experience in the area of immunology, with emphasis on inflammation, innate immunity and infectious diseases. Dr. Bozza has 95 publications in international journals (ex. J. Exp Med, Nat Med, J. Clin Invest, PNAS, Blood, FASEB, J Immunol, J Biol Chem), a H index of 38 and aprox. 5400 citations. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/7762134965139023

UNICAMP

Born in Taguatinga (Federal District), has obtained his Medical Degree by the University of Brasília (1999), Infectious Diseases Residency in the Tropical Medicine Foundation Dr. Heitor Vieira Dourado (FMT-HVD) (2002) and PhD in Tropical Medicine by the University of Brasília in partnership with the New York University (2007). He works as a physician in the FMT-HVD and as researcher at Instituto Leônidas & Maria Deane (FIOCRUZ-Amazonas), and also as a profesor of the Graduate Program on Tropical Medicine from the University of the Amazonas State, and adjunct professor at Kent State University. He is an expert in Infectious DIseases. He coordinates since 2017 the Institute of Clinical Research Carlos Borborema, in Manaus (Brazilian Amazon). He serves as an occasional consultant of the World Health Organization on Plasmodium vivax malaria. For some years he is actively involved in initiatives devoted to malaria elimination such as malERA, MESA and the Mesoamerica Initiative. He is also a member of the Expert Scientific Advisory Committee (ESAC) from Medicines for Malaria Venture (MMV) and WorldWide Antimalarial Resistance Network (WWARN). He has already supervised more than 50 undergraduate, master and PhD students, and pot-doctoral fellows, and has over 240 scientific publications in indexed journals. He is also a level 1 researcher from CNPq. H-index=38. Major research focuses: malaria, HIV, tuberculosis, snake bites accidents and emerging diseases. (Text informed by the author) CV Lattes: http://lattes.cnpq.br/8492376468047417

USP-ICB

Queen Mary University of London

Briefly describe why your experience and qualifications make you particularly well-suited for your role (e.g., PD/PI, mentor, participating faculty) in the project that is the subject of the application. Over the last decade my interests have evolved on the investigation of specific endogenous mediators and pathways (e.g. melanocortins, galectins, calcitonin and, more recently, resolvins and chemerin peptides) – mainly studied in the context of experimental and human arthritis, sepsis and reperfusion injury, all in all making an internationally recognised contribution to the resolution of inflammation research area. Presently, the focus of my research is on pro-resolving receptors attempting to understand their biology and define their signature to inform innovative therapeutic approaches to exploit the resolution concept - my long-term aim is to add Resolution Pharmacology to the textbooks of Pharmacology of next decade. To date, I have published over 350 peer-reviewed articles, with an H Factor of 91 and ~28,000 citations (Google Scholar).

Emory University School of Medicine

I am a physician/scientist with the requisite expertise, leadership skills, training, breadth of research experience, record of productivity and motivation necessary to successfully carry out the proposed research project. Providing medical care for children with unusual susceptibility to infections early in my career triggered an abiding interest in learning more about normal immune system development and function in order to explore the pathogenesis of immunological disorders, immunodeficiency diseases and lymphoid malignancies in particular. This interest has fueled my sustained effort to gain a deeper understanding of the basic organizing principles of the immune system with the goal of translational application of this information.

Radboud University

Mihai Netea was born and studied medicine in Cluj-Napoca, Romania. He completed his PhD at the Radboud University Nijmegen, The Netherlands, on studies investigating the cytokine network in sepsis. After working as a post-doc at the University of Colorado, he returned to Nijmegen where he finished his clinical training as an infectious diseases specialist, and where he currently heads the division of Experimental Medicine, Department of Internal Medicine, Nijmegen University Nijmegen Medical Center. He is mainly interested in understanding the factors influencing variability of human immune responses, the biology of sepsis and immunoparalysis in bacterial and fungal infections, and the study of the memory traits of innate immunity. He is the recipient of the Spinoza Prize 2016 and an ERC Advanced grant in 2019, and member of the Netherlands Royal Academy of Science (KNAW).

University of Massachusetts

My research is focused on understanding, in molecular detail, the mechanisms by which the innate immune response recognizes and responds to microbial challenge, as well as the mechanisms by which pathogens manipulate these responses for their own nefarious goals. Much of my research has focused on the favorite laboratory model insect, Drosophila melanogaster. This is a powerful approach because of the multitude of experimental techniques available to the Drosophila researcher, and because insects rely almost entirely on innate defenses for protection. Furthermore, the innate immune response evolved with some of the earliest metazoan creatures; consequently the insect immune response and the mammalian innate immune response utilize many highly conserved molecules, including NF-κB family transcription factors and their cognate signal transduction systems, as well as the Toll-like Receptors and CD36-like Receptors. Finally, the Drosophila immune response also serves as a model for the immune responses of other, more medically relevant insects such as the mosquito or sandfly. With colleagues and collaborators, I am regularly looking to translate basic discoveries made in the Drosophila model to mammalian systems, and the current proposal exemplifies this approach. This project is built upon results from Drosophila-based screens, detailed within the proposal. However, the entire research plan will utilize mammalian systems for more detailed studies.

USP-ICB

Graduated in Medicine from the Federal University of Ceará (1991), Master of Sciences in Medicine (Nephrology) from the Federal University of São Paulo (1997), specialization in Transplantation Immunology at the University of Tours (Diplome des Etudes Appronfodies, France, 1997-1999), PhD in Medicine (Nephrology) by the Federal University of São Paulo (2000), postdoc at Imperial College London (2000-2003) and habilitation (Livre Docencia) at the Federal University of São Paulo (Medicine) in 2006. He is currently full professor of Department of Immunology at the Institute of Biomedical Sciences at the University of São Paulo (since 2011). Visiting Professor at the University of Tours, France in 2006. The laboratory has experience in nephrology area and in cellular and applied immunology, acting on the following topics: kidney transplantation, experimental models of acute and chronic kidney diseases, ischemia and reperfusion injury, regulatory cells and stem cells in kidney diseases. More recently, the laboratory has been studying the microbiota interface, cellular metabolism and inflammation in models of autoimmunity and allo. Full member of São Paulo Research Academy.Full member of Brazilian Academy of Sciences. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/8098379714093877

NIH

I started my scientific career as a student of the Laboratory of Cellular and Molecular Immunology at Rene Rachou Institute – Fiocruz, Brazil, during my undergrad in Biomedicine. Got my master’s degree in Parasitology at the Biological Sciences Institute (ICB) of the Federal University of Minas Gerais – UFMG, Brazil. PhD in Parasitology from the ICB / UFMG, with one year of pre-doctoral training at the Laboratory of Parasitic Diseases (LPD) at the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), USA. This was followed by a consulting training at the Schistosomiasis Control Initiative (SCI) based at Imperial College - London, UK; where I then became a project manager/supervisor of the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) project in Cabo Delgado, Mozambique, managed by the University of Georgia–USA. After this training in coordinating public health programs and operational research in endemic areas in Africa, I then decided to start my postdoctoral training on helminth and host interaction. I am currently a postdoctoral fellow in the LPD, NIAID, NIH, USA. I have a broad background in immunology of parasitic infections and allergic diseases, biology of helminth parasites, and global health. My research interests include: 1) biomarkers for helminth antigen-specific T cells and immunophenotyping and transcriptome signature of Th2 cells; 2) mechanisms of human and experimental type-2 immune response induced by helminths; 3) influence of helminth infections on the regulation of the immune response of allergic individuals; 4) co-infections; and 5) implementation/monitoring/evaluation of different strategies of mass drug administration programs and diagnostics development for the control of Neglected Tropical Diseases in Africa.

UNICAMP

DVM - Universidade de Brasília (2006). Master - Allergology and Clinical Immunology - UFMUSP (2009). PhD in Immunology - Universidade de São Paulo (2011). Post doctoral at the Division of Endocrinology, Metabolism and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School. Professor in Immunology at the university of Campinas. The areas of research include: immunometabolism, diabetes and obesity. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/6667440528985761

Karolinska Institute

https://brodinlab.com/

University of Newcastle

UFS

Graduate at Medicina from Universidade Federal da Bahia (1985), master's at Immunology from Universidade Federal da Bahia (1990) and ph.d. at Immunology from Universidade Federal da Bahia (1997). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: l. braziliensis, leishmaniose tegumentar, cutaneous leishmaniasis, gm-csf and leishmania. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/9639889172454540

University of California

University of Massachusetts

UFMG-ICB

Graduate at Medicina from Universidade Federal da Bahia (1985), master's at Immunology from Universidade Federal da Bahia (1990) and ph.d. at Immunology from Universidade Federal da Bahia (1997). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: l. braziliensis, leishmaniose tegumentar, cutaneous leishmaniasis, gm-csf and leishmania. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/9639889172454540

BIOQMED-UFRJ

University of Massachusetts

Dr. Stuart M. Levitz is a Professor of Medicine and Microbiology & Physiological Systems at the University of Massachusetts Medical School. Dr. Levitz’s over 150 research publications have mostly focused on the mechanisms by which the immune system controls fungal pathogens and the strategies that fungi utilize to circumvent host defenses. Particular areas of interest include how fungal glycosylation influences immune responses, the mechanisms by which phagocytes exert antifungal activity and fungal vaccine development. Current areas of focus are the role of eosinophils in allergic airway disease and using glucan particles as a delivery system for Cryptococcus vaccines. Dr. Levitz also sees patients on the Transplant Infectious Diseases consultation service at UMassMemorial Hospital.

USP-FMRP

Has graduation at Farmácia-Bioquímica by Universidade de São Paulo (2003) , master's at Ciências Biológicas (Farmacologia) by Universidade de São Paulo (2005) , Ph.D. at Ciências Biológicas (Farmacologia) by Universidade de São Paulo (2008) , Postdoctorate by Harvard University (2019) and Postdoctorate by Universidade de São Paulo (2010) . Currently is of Universidade de São Paulo, of Universidade de São Paulo, of Universidade de São Paulo. Has experience in the area of Pharmacology , with emphasis on Farmacologia Geral. Focused, mainly, in the subjects: quimiocinas, prostaglandinas, TNFAlfa, hipernocicepção, CITOCINAS. (Text automatically generated by the application CVLattes). Link Lattes: http://lattes.cnpq.br/0585283327853481

BIONOVIS

Johannes Gutenberg-Universität Mainz

FIOCRUZ

USP-FMRP

Genentech

Vishva M. Dixit, M.D.
Vice President of Physiological Chemistry at Genentech, Inc. His interests include cell death, NF-kB signaling, role of ubiquitin modification in disease pathogenesis, and characterizing regulatory complexes within the innate immune system, especially, the Inflammasome. A historical perspective of his contributions is documented in three accounts published in Nature (2008, 453:271-273), Nature Cell Biology (2010, 12(5): 415) and The Journal of Immunology (2013, 190:3-4). He is a Foreign Member, European Molecular Biology Organization, a member of the National Academy of Medicine, the American Academy of Arts and Sciences and the National Academy of Sciences.

FIOCRUZ

(Frence), Doctor Honoris causa by Sorbonne Université (France) e the Luis Federico Leloir Medal (Argentinean government). He has expertise in Cellular Immunology, with emphasis in the following research areas: 1. Physiology of cell migration in the hemopoietic System; 2. Imimunoneuroendocrine interactions in health and diseases; 3) Lymphocyte migration and death in infectious diseases; 4. Lymphocyte migration in organ transplantation and autoimmune diseases; 5. Cell migration in leukemias and lymphomas; 6. Cell migration, cell therapy and immunotherapy in neuromuscular diseases. (Text informed by the author). Link Lattes: http://lattes.cnpq.br/1217083860799906