Program

OPENING SESSION

OPENING SESSION - CONFERENCE

Date: 26/09/2021

Time: 11:30 to 14:00

Room: 01

11:30 - 12:00

Chair Person - RICARDO GAZZINELLI - FIOCRUZ - PRESIDENT OF SBI (BRAZIL)

12:00 - 13:00

Measuring immunity doesn’t mean we understand protection

Speaker - ANDREW POLLARD - University of Oxford (UNITED KINGDOM)

13:00 - 14:00

Rapid COVID-19 Vaccine Development and the Future of Vaccinology

Speaker - BARNEY GRAHAM - NIAID/National Institutes of Health (UNITED STATES OF AMERICA)

SYMPOSIUM

SYMPOSIUM - 01 - INNATE SENSORS

Date: 26/09/2021

Time: 14:00 to 16:00

Room: 01

Chair Person - CAMILA INDIANI DE OLIVEIRA - FIOCRUZ (BRAZIL)

14:00 - 14:30

Induction of antiviral immunity by cGAS-like receptors in drosophila

Speaker - JEAN-LUC IMLER - Université de Strasbourg (FRANCE)

14:30 - 15:00

LAP and innate immune responses upon sensing of dying cells

Speaker - LARISSA CUNHA - FMRP/USP (BRAZIL)

15:00 - 15:30

An effector-triggered immune pathway in human monocytes

Speaker - RUSSELL VANCE - University of California (UNITED STATES OF AMERICA)

15:30 - 15:45

Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila

Short Talk - ISAQUE JOÃO DA SILVA DE FARIA - UFMG (BRAZIL)

15:45 - 16:00

Leishmania braziliensis exosomes induce the production of inflammatory mediators by mononuclear phagocytes through nlrp3 activation

Short Talk - FABIO DE CARVALHO PEIXOTO - FIOCRUZ (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 02 - SYSTEMS IMMUNOLOGY

Date: 26/09/2021

Time: 14:00 to 16:00

Room: 02

Chair Person - DANIEL MANSUR - UFSC (BRAZIL)

14:00 - 14:30

Systems Immunology of Inflammatory Diseases

Speaker - HELDER NAKAYA - Hospital Albert Einstein (BRAZIL)

14:30 - 15:00

Healthspan and lifespan : The Immune System takes the lead

Speaker - DAVID FURMAN - Buck Institute for Research on Aging (UNITED STATES OF AMERICA)

15:00 - 15:30

Microbiome regulation of Vaccines and Infections

Speaker - RAFICK-PIERRE SÉKALY - Emory University (UNITED STATES OF AMERICA)

SYMPOSIUM

SYMPOSIUM - 03 - IMMUNITY TO PARASITES

Date: 26/09/2021

Time: 17:00 to 19:00

Room: 01

Chair Person - VALÉRIA BORGES - FIOCRUZ (BRAZIL)

17:00 - 17:30

Immunopathogenesis and regulation of inflammatory response in cutaneous leishmaniasis due to Leishmania braziliensis infection

Speaker - LUCAS CARVALHO - UFBA (BRAZIL)

17:30 - 18:00

The control of Leishmania braziliensis-induced lesions

Speaker - JOÃO SANTANA SILVA - FIOCRUZ (BRAZIL)

18:00 - 18:30

T-cell responses in inflammatory cardiomyopathies of distinct etiologies

Speaker - WALDEREZ DUTRA - UFMG (BRAZIL)

18:30 - 18:45

Axl-receptor mediated efferocytosis inhibits immunity to Trypanosoma cruzi by blocking induction of m1 macrophages

Short Talk - THAÍS DA SILVA RIGONI - UFRJ (BRAZIL)

18:45 - 19:00

Extracellular traps from CD8+ and CD8- cells are distinct, and appear to have different functions in lesion from patients with cutaneous leishmaniasis.

Short Talk - CAROLINA CATTONI KOH - UFMG (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 04 - COVID19 VACCINES

Date: 26/09/2021

Time: 17:00 to 19:00

Room: 02

Chair Person - LUIS CARLOS DE SOUZA FERREIRA - USP (BRAZIL)

17:00 - 17:30

Development of a trivalent Covid-19 vaccine candidate based on the recombinant spike protein of SARS-COV-2 variants

Speaker - LEDA CASTILHO - UFRJ (BRAZIL)

17:30 - 18:00

Development a nasal spray  multivalent vaccine against COVID

Speaker - JORGE KALIL - FMUSP/INCOR (BRAZIL)

18:00 - 18:30

Digital evaluation of vaccine effectiveness.

Speaker - MANOEL BARRAL-NETTO - FIOCRUZ (BRAZIL)

18:30 - 18:45

Neutralizing antibody-independent immunity in rodent models of COVID19 immunized with a RBD/Nucleocapsid fusion protein

Short Talk - JULIA TEIXEIRA DE CASTRO - FMRP/USP (BRAZIL)

KEYNOTE

KEYNOTE - 01

Date: 26/09/2021

Time: 19:30 to 20:30

Room: 01

Chair Person - CLAUDIA IDA BRODSKYN - FIOCRUZ (BRAZIL)

19:30 - 20:30

P2RX7 signaling drives CD4+ T cell fate in infectious diseases

Speaker - MARIA REGINA D´IMPÉRIO LIMA - USP (BRAZIL)

MINI COURSE

MINI COURSE - SPONSORED BY BD

Date: 27/09/2021

Time: 09:00 to 10:00

Room: 01

09:00 - 10:00

Single Cell Multiomics (scMultiomics): Transcriptome and proteome of thousands of cells simultaneously

Speaker - IRIS CASTRO - BD

ORAL PRESENTATION

ORAL PRESENTATION - SBI-BD BIOSCIENCES AWARD

Date: 27/09/2021

Time: 10:00 to 12:00

Room: 01

Chair Person - ANA PAULA LEPIQUE - USP (BRAZIL)

SYMPOSIUM

SYMPOSIUM - SPONSORED BY THERMOFISHER

Date: 27/09/2021

Time: 12:00 to 13:00

Room: 01

Chair Person - FLÁVIA MESQUITA - Market Development Specialist

ATTUNE CYTPIX FLOW CYTOMETER: TAKE A BETTER LOOK AT YOUR CELLS

Speaker - LUCAS RIZZO - Field Application Specialist (FAS) and Technical Sales Specialist (TSS)

KEYNOTE

KEYNOTE - 02

Date: 27/09/2021

Time: 13:00 to 13:50

Room: 01

Chair Person - KELLY MAGALHÃES - UNB (BRAZIL)

13:00 - 13:50

Metabolic targeting in inflammation and immunothrombosis

Speaker - LUKE O'NEILL - Trinity College Dublin (IRELAND)

SYMPOSIUM

SYMPOSIUM - 05 - LYMPHOCYTE BIOLOGY

Date: 27/09/2021

Time: 14:00 to 16:00

Room: 01

Chair Person - MARIA REGINA D´IMPÉRIO LIMA - USP (BRAZIL)

14:00 - 14:30

New insights into malaria blood stage immunity

Speaker - CAROLINE JUNQUEIRA - FIOCRUZ (BRAZIL)

14:30 - 15:00

Non-canonical roles for metabolic enzymes in Th17 differentiation and function

Speaker - JOSÉ CARLOS ALVES-FILHO - FMRP/USP (BRAZIL)

15:00 - 15:30

New insights in conventional and invariant T cells immunobiology

Speaker - MARCO ATAIDE - FMRP/USP (BRAZIL)

15:30 - 15:45

P2X7 receptor controls the function of T follicular regulatory cells in experimental malaria

Short Talk - PAULO HENRIQUE LISBOA RAEDER - USP (BRAZIL)

15:45 - 16:00

Hepatic B cells change their morphology and maturation state during liver neonatal development

Short Talk - KASSIANA MAFRA BICALHO - UFMG (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 06 - TUMOR IMMUNOLOGY

Date: 27/09/2021

Time: 14:00 to 16:00

Room: 02

Chair Person - KELEN CRISTINA RIBEIRO MALMEGRIM DE FARIAS - FCFRP/USP (BRAZIL)

14:00 - 14:30

Lipid droplets: platforms with multiple functions in cancer hallmarks

Speaker - JOÃO VIOLA - INCA (BRAZIL)

14:30 - 15:00

An innate axis for PD-1 mediated Immunosuppression

Speaker - CRISTINA BONORINO - UFCSPA (BRAZIL)

15:00 - 15:30

Epigenetic therapy in immune-oncology

Speaker - DANIEL DE CARVALHO - UHN Research (CANADA)

15:30 - 15:45

Role of Tumor-Associated Tissue Eosinophilia (TATE) in Murine Triple-Negative Breast Cancer

Short Talk - DIEGO CARLOS REIS - UFMG (BRAZIL)

15:45 - 16:00

Inflammasome assessment in Sézary's Syndrome

Short Talk - FERNANDA CARDOSO - USP (BRAZIL)

SYMPOSIUM

SYMPOSIUM - SPONSORED BY ASTRAZENECA

Date: 27/09/2021

Time: 16:00 to 17:00

Room: 01

Chair Person - BARBARA FURTADO

16:00 - 17:00

Overview of COVID-19 vaccines: What do we know an what is the future impact?

Speaker - MARCO SAFADI

SYMPOSIUM

SYMPOSIUM - 07 - HOST RESPONSE TO BACTERIA

Date: 27/09/2021

Time: 17:00 to 19:00

Room: 01

Chair Person - ALEXANDRA IVO MEDEIROS - UNESP (BRAZIL)

17:00 - 17:30

Suppression of host immunity by Coxiella burnetii

Speaker - CRAIG ROY - Yale School of Medicine (UNITED STATES OF AMERICA)

17:30 - 18:00

Causes and consequences of gut dysbiosis

Speaker - ANDREAS BAUMLER - UC Davis School Of Medicine (UNITED STATES OF AMERICA)

18:00 - 18:30

STING regulates metabolic reprogramming in macrophages via HIF-1α pathway during bacterial infection.

Speaker - SERGIO COSTA OLIVEIRA - UFMG (BRAZIL)

18:30 - 18:45

Temperature-dependent reprogramming of bacterial clearance by neutrophils versus macrophages

Short Talk - MONIQUE T. FONSECA - USP (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 08 - IMMUNOMETABOLISM

Date: 27/09/2021

Time: 17:00 to 19:00

Room: 02

17:00 - 17:00

Chair Person - VÂNIA LUIZA DEPERON BONATO - FMRP-USP (BRAZIL)

17:00 - 17:30

Targeting mitochondrial metabolism to influence T cell differentiation and function

Speaker - TIM SPARWASSER - University Medical Center of Mainz (GERMANY)

17:30 - 18:00

SCFAs and HIF-1 as key regulators of gut microbiota and host interactions

Speaker - MARCO AURÉLIO RAMIREZ VINOLO - Unicamp (BRAZIL)

18:00 - 18:30

Control of CD8+ T cell immunity by extracellular ATP sensing and export

Speaker - HENRIQUE BORGES DA SILVA - Mayo Clinic (UNITED STATES OF AMERICA)

18:30 - 18:45

Glycolysis governs dendritic cell activation after efferocytosis of Staphylococcus aureus-infected apoptotic cells.

Short Talk - LETÍCIA DE AQUINO PENTEADO - FMRP-USP (BRAZIL)

18:45 - 19:00

The immunometabolic status of monocyte-derived dendritic cells is sustained by pparg-induced glucose metabolism in plasmodium infection

Short Talk - THERESA RAMALHO - UMMS (UNITED STATES OF AMERICA)

KEYNOTE

KEYNOTE - 03

Date: 27/09/2021

Time: 19:30 to 20:30

Room: 01

Chair Person - ANA PAULA JUNQUEIRA-KIPNIS - UFG (BRAZIL)

19:30 - 20:30

Regulation of antiviral defenses by the mosquito virome

Speaker - JOÃO T. MARQUES - UFMG (BRAZIL)

ASSEMBLY GENERAL

ASSEMBLY GENERAL - SBI GENERAL ASSEMBLY

Date: 28/09/2021

Time: 08:30 to 10:00

Room: SBI ZOOM

Link: https://us06web.zoom.us/j/81764469153

ID da reunião: 817 6446 9153

MINI COURSE

MINI COURSE - SPONSORED BY BD

Date: 28/09/2021

Time: 09:00 to 10:00

Room: 01

09:00 - 10:00

Cytometry and panel design: all you need to know to perform a successful immunophenotyping

Speaker - NAYANE GALDINO - BD

ORAL PRESENTATION

ORAL PRESENTATION - THEREZA KIPNIS AWARD

Date: 28/09/2021

Time: 09:30 to 13:00

Room: 02

Chair Person - ANDRÉ MACEDO VALE - URFJ (BRAZIL)

Chair Person - MARCELO TORRES BOZZA - UFRJ (BRAZIL)

1. The transcriptional cofactor IRF2BP2 plays a key role in T cell homeostasis, IFN-gamma production and FoxP3+ T cell expansion

Speaker - BARBARA LUCIA MORAIS DE OLIVEIRA VIEIRA (BRAZIL)

2. Adenosine derived from expanded cd39-expressing plasmablasts mediates immunosuppression after sepsis by inhibiting macrophage microbial killing

Speaker - DANIELE CARVALHO BERNARDO NASCIMENTO (BRAZIL)

3. Targeting Neutrophil Extracellular Traps ameliorates COVID-19 immunopathology

Speaker - FLÁVIO PROTÁSIO VERAS (BRAZIL)

4. HIF-1α-mediated mitochondrial metabolic adaptation is essential for M1 macrophage response

Speaker - GUSTAVO GASTÃO DAVANZO (BRAZIL)

5. The extracellular atp sensor p2rx7 exacerbates lung inflammation through establishment of tissue resident-cd4+ t cells in response to lung-tropic infections

Speaker - IGOR SANTIAGO-CARVALHO - University of São Paulo (BRAZIL)

6. Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism

Speaker - JOSÉ LUÍS FACHI - UNICAMP (BRAZIL)

6. SARS-CoV-2 Uses CD4 to Infect T Helper Lymphocytes

Speaker - NATÁLIA BRUNETTI SILVA (BRAZIL)

8. Inflammasomes are activated in response to sars-cov-2 infection and are associated with covid-19 severity in patients

Speaker - TAMARA SIVA RODRIGUES (BRAZIL)

SYMPOSIUM

SYMPOSIUM - SPONSORED BY GSK

Date: 28/09/2021

Time: 12:00 to 13:00

Room: 01

Chair Person - MARTTI ANTILA - ProAr

12:00 - 13:00

Atualização dos imunobiológicos no tratamento da COVID-19

Speaker - DIEGO FALCI - HCPA/UFRGS

KEYNOTE

KEYNOTE - 04

Date: 28/09/2021

Time: 13:00 to 13:50

Room: 01

Chair Person - GUSTAVO P. AMARANTE-MENDES - USP (BRAZIL)

13:00 - 13:50

Homeostatic and pathogenic cell interactions at the gut microbiota-mucosa interface

Speaker - DAN LITTMAN - New York University (UNITED STATES OF AMERICA)

SYMPOSIUM

SYMPOSIUM - 09 - IMMUNITY TO MICROBIOTA AND HELMINTH INFECTIONS

Date: 28/09/2021

Time: 14:00 to 16:00

Room: 01

Chair Person - ANA MARIA CAETANO FARIA - UFMG (BRAZIL)

14:00 - 14:30

The gut-lung axis during long Covid-19: the role of gut microbiota on the post Covid effects

Speaker - ANGELICA THOMAZ VIEIRA - UFMG (BRAZIL)

14:30 - 15:00

The weaning reaction and immunological imprinting

Speaker - GÉRARD EBERL - Institut Pasteur (FRANCE)

15:00 - 15:30

Role of microbiota and short-chain fatty acids during respiratory viral infection

Speaker - ANA PAULA DUARTE DE SOUZA - PUCRS (BRAZIL)

15:30 - 16:00

Interaction between allergen- and helminth-driven type-2 immune responses

Speaker - PEDRO GAZZINELLI - National Institutes of Health - National Institute of Allergy and Infectious Disease (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 10 - NEUROINFLAMMATION

Date: 28/09/2021

Time: 14:00 to 16:00

Room: 02

Chair Person - ALEXANDRE SALGADO BASSO - UNIFESP (BRAZIL)

14:00 - 14:30

NLRP3 inflammasome activation in Alzheimer’s disease

Speaker - MICHAEL T. HENEKA - University of Bonn (GERMANY)

14:30 - 15:00

Defective hormonal signaling in Alzheimer’s disease

Speaker - FERNANDA FELICE - UFRJ (BRAZIL)

15:00 - 15:30

Mediators of Immunopathology: the Monocyte to Phagocyte Transition in Inflammation

Speaker - BURKHARD BECHER - University of Zurich (GERMANY)

15:30 - 15:45

Reduced neuroinflammation, energetic metabolic shifting, and epigenetic reprogramming mediate hippocampal neuroregeneration in an ex vivo model of thiamine deficiency

Short Talk - LARISSA MARCELY GOMES CASSIANO - UFMG (BRAZIL)

15:45 - 16:00

STAT5/Runx3 Axis Favors the Cytotoxic Activity of Pathogenic CD4 T Cells During the Early Stage of Autoimmune Neuroinflammation

Short Talk - ANA MARIA MARQUES - UNICAMP (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 11 - MUCOSAL IMMUNOLOGY

Date: 28/09/2021

Time: 17:00 to 19:00

Room: 01

Chair Person - DENISE MORAIS DA FONSECA - ICB/USP (BRAZIL)

17:00 - 17:30

Crosstalk between epithelium and regulatory T cells in the lung

Speaker - LUCAS D. FAUSTINO - Massachusetts General Hospital - Center for Immunology and Inflammatory Diseases (UNITED STATES OF AMERICA)

17:30 - 18:00

Intestinal tuft cell inflammasome activation leads to prostaglandin D2 release and an antibacterial response

Speaker - ISABELLA RAUCH - Oregon Health & Science University (OHSU)

18:00 - 18:30

Regulation of Mucosal Immunity by immune-endocrine interactions

Speaker - CRISTINA RIBEIRO DE BARROS CARDOSO - FMRP-USP (BRAZIL)

18:30 - 18:45

Acetate triggers antiviral response through modulation of RIG-I expression in cells from infants with Respiratory Syncytial Virus bronchiolitis

Short Talk - KRIST HELEN ANTUNES - PUCRS (BRAZIL)

18:45 - 19:00

Obesity associated with hyperglycemia impairs oral tolerance induction and aggravated food allergy

Short Talk - LÍCIA TORRES - UFMG (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 12 - COVID-19

Date: 28/09/2021

Time: 17:00 to 19:00

Room: 02

Chair Person - FERNANDO Q CUNHA - FMRP-USP (BRAZIL)

17:00 - 17:30

Immunometabolism and metabolic diseases associated with COVID-19

Speaker - PEDRO M. M. M. VIEIRA - Unicamp (BRAZIL)

17:30 - 18:00

Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

Speaker - PATRÍCIA T. BOZZA - FIOCRUZ (BRAZIL)

18:00 - 18:30

Inflammasomes in the pathophysiology of COVID-19

Speaker - DARIO S. ZAMBONI - FMRP/USP (BRAZIL)

18:30 - 18:45

Antibody IGG production in convalescent patients of SARS-COV-2 infection in Manaus

Short Talk - ALEXANDER LEONARDO SILVA JUNIOR - UFAM (BRAZIL)

18:45 - 19:00

Cytokines and anaphylotoxins profile from COVID-19 patients in Alagoas, Brazil (May - September, 2020)

Short Talk - RAYANE MARTINS BOTELHO - UFAL (BRAZIL)

CLOSING

CLOSING - CONFERENCE

Date: 28/09/2021

Time: 19:30 to 20:30

Room: 01

Chair Person - KARINA RAMALHO BORTOLUCI - UNIFESP (BRAZIL)

19:30 - 20:30

Why so Many Ways to Die? The non-canonical Inflammasome Pathway

Speaker - VISHVA M. DIXIT - Genentech Inc (UNITED STATES OF AMERICA)

CLOSING

CLOSING - REMARKS, AWARDS ANNOUNCEMENT, AND FUN

Date: 28/09/2021

Time: 20:30 to 21:30

Room: 01

Board of SBI

OPENING SESSION

OPENING SESSION - CONFERENCE

Date: 26/09/2021

Time: 11:30 to 14:00

Room: 01

11:30 - 12:00

Chair Person - RICARDO GAZZINELLI - FIOCRUZ - PRESIDENT OF SBI (BRAZIL)

12:00 - 13:00

Measuring immunity doesn’t mean we understand protection

Speaker - ANDREW POLLARD - University of Oxford (UNITED KINGDOM)

13:00 - 14:00

Rapid COVID-19 Vaccine Development and the Future of Vaccinology

Speaker - BARNEY GRAHAM - NIAID/National Institutes of Health (UNITED STATES OF AMERICA)

SYMPOSIUM

SYMPOSIUM - 01 - INNATE SENSORS

Date: 26/09/2021

Time: 14:00 to 16:00

Room: 01

Chair Person - CAMILA INDIANI DE OLIVEIRA - FIOCRUZ (BRAZIL)

14:00 - 14:30

Induction of antiviral immunity by cGAS-like receptors in drosophila

Speaker - JEAN-LUC IMLER - Université de Strasbourg (FRANCE)

14:30 - 15:00

LAP and innate immune responses upon sensing of dying cells

Speaker - LARISSA CUNHA - FMRP/USP (BRAZIL)

15:00 - 15:30

An effector-triggered immune pathway in human monocytes

Speaker - RUSSELL VANCE - University of California (UNITED STATES OF AMERICA)

15:30 - 15:45

Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila

Short Talk - ISAQUE JOÃO DA SILVA DE FARIA - UFMG (BRAZIL)

15:45 - 16:00

Leishmania braziliensis exosomes induce the production of inflammatory mediators by mononuclear phagocytes through nlrp3 activation

Short Talk - FABIO DE CARVALHO PEIXOTO - FIOCRUZ (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 03 - IMMUNITY TO PARASITES

Date: 26/09/2021

Time: 17:00 to 19:00

Room: 01

Chair Person - VALÉRIA BORGES - FIOCRUZ (BRAZIL)

17:00 - 17:30

Immunopathogenesis and regulation of inflammatory response in cutaneous leishmaniasis due to Leishmania braziliensis infection

Speaker - LUCAS CARVALHO - UFBA (BRAZIL)

17:30 - 18:00

The control of Leishmania braziliensis-induced lesions

Speaker - JOÃO SANTANA SILVA - FIOCRUZ (BRAZIL)

18:00 - 18:30

T-cell responses in inflammatory cardiomyopathies of distinct etiologies

Speaker - WALDEREZ DUTRA - UFMG (BRAZIL)

18:30 - 18:45

Axl-receptor mediated efferocytosis inhibits immunity to Trypanosoma cruzi by blocking induction of m1 macrophages

Short Talk - THAÍS DA SILVA RIGONI - UFRJ (BRAZIL)

18:45 - 19:00

Extracellular traps from CD8+ and CD8- cells are distinct, and appear to have different functions in lesion from patients with cutaneous leishmaniasis.

Short Talk - CAROLINA CATTONI KOH - UFMG (BRAZIL)

KEYNOTE

KEYNOTE - 01

Date: 26/09/2021

Time: 19:30 to 20:30

Room: 01

Chair Person - CLAUDIA IDA BRODSKYN - FIOCRUZ (BRAZIL)

19:30 - 20:30

P2RX7 signaling drives CD4+ T cell fate in infectious diseases

Speaker - MARIA REGINA D´IMPÉRIO LIMA - USP (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 02 - SYSTEMS IMMUNOLOGY

Date: 26/09/2021

Time: 14:00 to 16:00

Room: 02

Chair Person - DANIEL MANSUR - UFSC (BRAZIL)

14:00 - 14:30

Systems Immunology of Inflammatory Diseases

Speaker - HELDER NAKAYA - Hospital Albert Einstein (BRAZIL)

14:30 - 15:00

Healthspan and lifespan : The Immune System takes the lead

Speaker - DAVID FURMAN - Buck Institute for Research on Aging (UNITED STATES OF AMERICA)

15:00 - 15:30

Microbiome regulation of Vaccines and Infections

Speaker - RAFICK-PIERRE SÉKALY - Emory University (UNITED STATES OF AMERICA)

SYMPOSIUM

SYMPOSIUM - 04 - COVID19 VACCINES

Date: 26/09/2021

Time: 17:00 to 19:00

Room: 02

Chair Person - LUIS CARLOS DE SOUZA FERREIRA - USP (BRAZIL)

17:00 - 17:30

Development of a trivalent Covid-19 vaccine candidate based on the recombinant spike protein of SARS-COV-2 variants

Speaker - LEDA CASTILHO - UFRJ (BRAZIL)

17:30 - 18:00

Development a nasal spray  multivalent vaccine against COVID

Speaker - JORGE KALIL - FMUSP/INCOR (BRAZIL)

18:00 - 18:30

Digital evaluation of vaccine effectiveness.

Speaker - MANOEL BARRAL-NETTO - FIOCRUZ (BRAZIL)

18:30 - 18:45

Neutralizing antibody-independent immunity in rodent models of COVID19 immunized with a RBD/Nucleocapsid fusion protein

Short Talk - JULIA TEIXEIRA DE CASTRO - FMRP/USP (BRAZIL)

MINI COURSE

MINI COURSE - SPONSORED BY BD

Date: 27/09/2021

Time: 09:00 to 10:00

Room: 01

09:00 - 10:00

Single Cell Multiomics (scMultiomics): Transcriptome and proteome of thousands of cells simultaneously

Speaker - IRIS CASTRO - BD

ORAL PRESENTATION

ORAL PRESENTATION - SBI-BD BIOSCIENCES AWARD

Date: 27/09/2021

Time: 10:00 to 12:00

Room: 01

Chair Person - ANA PAULA LEPIQUE - USP (BRAZIL)

SYMPOSIUM

SYMPOSIUM - SPONSORED BY THERMOFISHER

Date: 27/09/2021

Time: 12:00 to 13:00

Room: 01

Chair Person - FLÁVIA MESQUITA - Market Development Specialist

ATTUNE CYTPIX FLOW CYTOMETER: TAKE A BETTER LOOK AT YOUR CELLS

Speaker - LUCAS RIZZO - Field Application Specialist (FAS) and Technical Sales Specialist (TSS)

KEYNOTE

KEYNOTE - 02

Date: 27/09/2021

Time: 13:00 to 13:50

Room: 01

Chair Person - KELLY MAGALHÃES - UNB (BRAZIL)

13:00 - 13:50

Metabolic targeting in inflammation and immunothrombosis

Speaker - LUKE O'NEILL - Trinity College Dublin (IRELAND)

SYMPOSIUM

SYMPOSIUM - 05 - LYMPHOCYTE BIOLOGY

Date: 27/09/2021

Time: 14:00 to 16:00

Room: 01

Chair Person - MARIA REGINA D´IMPÉRIO LIMA - USP (BRAZIL)

14:00 - 14:30

New insights into malaria blood stage immunity

Speaker - CAROLINE JUNQUEIRA - FIOCRUZ (BRAZIL)

14:30 - 15:00

Non-canonical roles for metabolic enzymes in Th17 differentiation and function

Speaker - JOSÉ CARLOS ALVES-FILHO - FMRP/USP (BRAZIL)

15:00 - 15:30

New insights in conventional and invariant T cells immunobiology

Speaker - MARCO ATAIDE - FMRP/USP (BRAZIL)

15:30 - 15:45

P2X7 receptor controls the function of T follicular regulatory cells in experimental malaria

Short Talk - PAULO HENRIQUE LISBOA RAEDER - USP (BRAZIL)

15:45 - 16:00

Hepatic B cells change their morphology and maturation state during liver neonatal development

Short Talk - KASSIANA MAFRA BICALHO - UFMG (BRAZIL)

SYMPOSIUM

SYMPOSIUM - SPONSORED BY ASTRAZENECA

Date: 27/09/2021

Time: 16:00 to 17:00

Room: 01

Chair Person - BARBARA FURTADO

16:00 - 17:00

Overview of COVID-19 vaccines: What do we know an what is the future impact?

Speaker - MARCO SAFADI

SYMPOSIUM

SYMPOSIUM - 07 - HOST RESPONSE TO BACTERIA

Date: 27/09/2021

Time: 17:00 to 19:00

Room: 01

Chair Person - ALEXANDRA IVO MEDEIROS - UNESP (BRAZIL)

17:00 - 17:30

Suppression of host immunity by Coxiella burnetii

Speaker - CRAIG ROY - Yale School of Medicine (UNITED STATES OF AMERICA)

17:30 - 18:00

Causes and consequences of gut dysbiosis

Speaker - ANDREAS BAUMLER - UC Davis School Of Medicine (UNITED STATES OF AMERICA)

18:00 - 18:30

STING regulates metabolic reprogramming in macrophages via HIF-1α pathway during bacterial infection.

Speaker - SERGIO COSTA OLIVEIRA - UFMG (BRAZIL)

18:30 - 18:45

Temperature-dependent reprogramming of bacterial clearance by neutrophils versus macrophages

Short Talk - MONIQUE T. FONSECA - USP (BRAZIL)

KEYNOTE

KEYNOTE - 03

Date: 27/09/2021

Time: 19:30 to 20:30

Room: 01

Chair Person - ANA PAULA JUNQUEIRA-KIPNIS - UFG (BRAZIL)

19:30 - 20:30

Regulation of antiviral defenses by the mosquito virome

Speaker - JOÃO T. MARQUES - UFMG (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 06 - TUMOR IMMUNOLOGY

Date: 27/09/2021

Time: 14:00 to 16:00

Room: 02

Chair Person - KELEN CRISTINA RIBEIRO MALMEGRIM DE FARIAS - FCFRP/USP (BRAZIL)

14:00 - 14:30

Lipid droplets: platforms with multiple functions in cancer hallmarks

Speaker - JOÃO VIOLA - INCA (BRAZIL)

14:30 - 15:00

An innate axis for PD-1 mediated Immunosuppression

Speaker - CRISTINA BONORINO - UFCSPA (BRAZIL)

15:00 - 15:30

Epigenetic therapy in immune-oncology

Speaker - DANIEL DE CARVALHO - UHN Research (CANADA)

15:30 - 15:45

Role of Tumor-Associated Tissue Eosinophilia (TATE) in Murine Triple-Negative Breast Cancer

Short Talk - DIEGO CARLOS REIS - UFMG (BRAZIL)

15:45 - 16:00

Inflammasome assessment in Sézary's Syndrome

Short Talk - FERNANDA CARDOSO - USP (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 08 - IMMUNOMETABOLISM

Date: 27/09/2021

Time: 17:00 to 19:00

Room: 02

17:00 - 17:00

Chair Person - VÂNIA LUIZA DEPERON BONATO - FMRP-USP (BRAZIL)

17:00 - 17:30

Targeting mitochondrial metabolism to influence T cell differentiation and function

Speaker - TIM SPARWASSER - University Medical Center of Mainz (GERMANY)

17:30 - 18:00

SCFAs and HIF-1 as key regulators of gut microbiota and host interactions

Speaker - MARCO AURÉLIO RAMIREZ VINOLO - Unicamp (BRAZIL)

18:00 - 18:30

Control of CD8+ T cell immunity by extracellular ATP sensing and export

Speaker - HENRIQUE BORGES DA SILVA - Mayo Clinic (UNITED STATES OF AMERICA)

18:30 - 18:45

Glycolysis governs dendritic cell activation after efferocytosis of Staphylococcus aureus-infected apoptotic cells.

Short Talk - LETÍCIA DE AQUINO PENTEADO - FMRP-USP (BRAZIL)

18:45 - 19:00

The immunometabolic status of monocyte-derived dendritic cells is sustained by pparg-induced glucose metabolism in plasmodium infection

Short Talk - THERESA RAMALHO - UMMS (UNITED STATES OF AMERICA)

ASSEMBLY GENERAL

ASSEMBLY GENERAL - SBI GENERAL ASSEMBLY

Date: 28/09/2021

Time: 08:30 to 10:00

Room: SBI ZOOM

Link: https://us06web.zoom.us/j/81764469153

ID da reunião: 817 6446 9153

MINI COURSE

MINI COURSE - SPONSORED BY BD

Date: 28/09/2021

Time: 09:00 to 10:00

Room: 01

09:00 - 10:00

Cytometry and panel design: all you need to know to perform a successful immunophenotyping

Speaker - NAYANE GALDINO - BD

SYMPOSIUM

SYMPOSIUM - SPONSORED BY GSK

Date: 28/09/2021

Time: 12:00 to 13:00

Room: 01

Chair Person - MARTTI ANTILA - ProAr

12:00 - 13:00

Atualização dos imunobiológicos no tratamento da COVID-19

Speaker - DIEGO FALCI - HCPA/UFRGS

KEYNOTE

KEYNOTE - 04

Date: 28/09/2021

Time: 13:00 to 13:50

Room: 01

Chair Person - GUSTAVO P. AMARANTE-MENDES - USP (BRAZIL)

13:00 - 13:50

Homeostatic and pathogenic cell interactions at the gut microbiota-mucosa interface

Speaker - DAN LITTMAN - New York University (UNITED STATES OF AMERICA)

SYMPOSIUM

SYMPOSIUM - 09 - IMMUNITY TO MICROBIOTA AND HELMINTH INFECTIONS

Date: 28/09/2021

Time: 14:00 to 16:00

Room: 01

Chair Person - ANA MARIA CAETANO FARIA - UFMG (BRAZIL)

14:00 - 14:30

The gut-lung axis during long Covid-19: the role of gut microbiota on the post Covid effects

Speaker - ANGELICA THOMAZ VIEIRA - UFMG (BRAZIL)

14:30 - 15:00

The weaning reaction and immunological imprinting

Speaker - GÉRARD EBERL - Institut Pasteur (FRANCE)

15:00 - 15:30

Role of microbiota and short-chain fatty acids during respiratory viral infection

Speaker - ANA PAULA DUARTE DE SOUZA - PUCRS (BRAZIL)

15:30 - 16:00

Interaction between allergen- and helminth-driven type-2 immune responses

Speaker - PEDRO GAZZINELLI - National Institutes of Health - National Institute of Allergy and Infectious Disease (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 11 - MUCOSAL IMMUNOLOGY

Date: 28/09/2021

Time: 17:00 to 19:00

Room: 01

Chair Person - DENISE MORAIS DA FONSECA - ICB/USP (BRAZIL)

17:00 - 17:30

Crosstalk between epithelium and regulatory T cells in the lung

Speaker - LUCAS D. FAUSTINO - Massachusetts General Hospital - Center for Immunology and Inflammatory Diseases (UNITED STATES OF AMERICA)

17:30 - 18:00

Intestinal tuft cell inflammasome activation leads to prostaglandin D2 release and an antibacterial response

Speaker - ISABELLA RAUCH - Oregon Health & Science University (OHSU)

18:00 - 18:30

Regulation of Mucosal Immunity by immune-endocrine interactions

Speaker - CRISTINA RIBEIRO DE BARROS CARDOSO - FMRP-USP (BRAZIL)

18:30 - 18:45

Acetate triggers antiviral response through modulation of RIG-I expression in cells from infants with Respiratory Syncytial Virus bronchiolitis

Short Talk - KRIST HELEN ANTUNES - PUCRS (BRAZIL)

18:45 - 19:00

Obesity associated with hyperglycemia impairs oral tolerance induction and aggravated food allergy

Short Talk - LÍCIA TORRES - UFMG (BRAZIL)

CLOSING

CLOSING - CONFERENCE

Date: 28/09/2021

Time: 19:30 to 20:30

Room: 01

Chair Person - KARINA RAMALHO BORTOLUCI - UNIFESP (BRAZIL)

19:30 - 20:30

Why so Many Ways to Die? The non-canonical Inflammasome Pathway

Speaker - VISHVA M. DIXIT - Genentech Inc (UNITED STATES OF AMERICA)

CLOSING

CLOSING - REMARKS, AWARDS ANNOUNCEMENT, AND FUN

Date: 28/09/2021

Time: 20:30 to 21:30

Room: 01

Board of SBI

ORAL PRESENTATION

ORAL PRESENTATION - THEREZA KIPNIS AWARD

Date: 28/09/2021

Time: 09:30 to 13:00

Room: 02

Chair Person - ANDRÉ MACEDO VALE - URFJ (BRAZIL)

Chair Person - MARCELO TORRES BOZZA - UFRJ (BRAZIL)

1. The transcriptional cofactor IRF2BP2 plays a key role in T cell homeostasis, IFN-gamma production and FoxP3+ T cell expansion

Speaker - BARBARA LUCIA MORAIS DE OLIVEIRA VIEIRA (BRAZIL)

2. Adenosine derived from expanded cd39-expressing plasmablasts mediates immunosuppression after sepsis by inhibiting macrophage microbial killing

Speaker - DANIELE CARVALHO BERNARDO NASCIMENTO (BRAZIL)

3. Targeting Neutrophil Extracellular Traps ameliorates COVID-19 immunopathology

Speaker - FLÁVIO PROTÁSIO VERAS (BRAZIL)

4. HIF-1α-mediated mitochondrial metabolic adaptation is essential for M1 macrophage response

Speaker - GUSTAVO GASTÃO DAVANZO (BRAZIL)

5. The extracellular atp sensor p2rx7 exacerbates lung inflammation through establishment of tissue resident-cd4+ t cells in response to lung-tropic infections

Speaker - IGOR SANTIAGO-CARVALHO - University of São Paulo (BRAZIL)

6. Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism

Speaker - JOSÉ LUÍS FACHI - UNICAMP (BRAZIL)

6. SARS-CoV-2 Uses CD4 to Infect T Helper Lymphocytes

Speaker - NATÁLIA BRUNETTI SILVA (BRAZIL)

8. Inflammasomes are activated in response to sars-cov-2 infection and are associated with covid-19 severity in patients

Speaker - TAMARA SIVA RODRIGUES (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 10 - NEUROINFLAMMATION

Date: 28/09/2021

Time: 14:00 to 16:00

Room: 02

Chair Person - ALEXANDRE SALGADO BASSO - UNIFESP (BRAZIL)

14:00 - 14:30

NLRP3 inflammasome activation in Alzheimer’s disease

Speaker - MICHAEL T. HENEKA - University of Bonn (GERMANY)

14:30 - 15:00

Defective hormonal signaling in Alzheimer’s disease

Speaker - FERNANDA FELICE - UFRJ (BRAZIL)

15:00 - 15:30

Mediators of Immunopathology: the Monocyte to Phagocyte Transition in Inflammation

Speaker - BURKHARD BECHER - University of Zurich (GERMANY)

15:30 - 15:45

Reduced neuroinflammation, energetic metabolic shifting, and epigenetic reprogramming mediate hippocampal neuroregeneration in an ex vivo model of thiamine deficiency

Short Talk - LARISSA MARCELY GOMES CASSIANO - UFMG (BRAZIL)

15:45 - 16:00

STAT5/Runx3 Axis Favors the Cytotoxic Activity of Pathogenic CD4 T Cells During the Early Stage of Autoimmune Neuroinflammation

Short Talk - ANA MARIA MARQUES - UNICAMP (BRAZIL)

SYMPOSIUM

SYMPOSIUM - 12 - COVID-19

Date: 28/09/2021

Time: 17:00 to 19:00

Room: 02

Chair Person - FERNANDO Q CUNHA - FMRP-USP (BRAZIL)

17:00 - 17:30

Immunometabolism and metabolic diseases associated with COVID-19

Speaker - PEDRO M. M. M. VIEIRA - Unicamp (BRAZIL)

17:30 - 18:00

Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

Speaker - PATRÍCIA T. BOZZA - FIOCRUZ (BRAZIL)

18:00 - 18:30

Inflammasomes in the pathophysiology of COVID-19

Speaker - DARIO S. ZAMBONI - FMRP/USP (BRAZIL)

18:30 - 18:45

Antibody IGG production in convalescent patients of SARS-COV-2 infection in Manaus

Short Talk - ALEXANDER LEONARDO SILVA JUNIOR - UFAM (BRAZIL)

18:45 - 19:00

Cytokines and anaphylotoxins profile from COVID-19 patients in Alagoas, Brazil (May - September, 2020)

Short Talk - RAYANE MARTINS BOTELHO - UFAL (BRAZIL)

SESSION – POSTER

Date: September 26 to 28
The E-Posters will be available on the congress platform during the entire congress, but there is no specific time that the E-Poster presenters are required to be online. Participants will be able to contact the presenter and ask questions during the virtual congress.